November 01, 2014 at 03:35AM Marathon Ventures, Inc. Announces Voluntary Recall of Raw Macadamia Nuts Due to Possible Health Risk

Marathon Ventures, Inc. announced today that it is voluntarily recalling various retail and bulk packages containing raw macadamia nuts as a precautionary measure because the product may be contaminated with Salmonella, an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems. Healthy persons infected with Salmonella often experience fever, nausea, vomiting, diarrhea (which may be bloody), and abdominal pain.



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October 31, 2014 at 11:22PM Farewell letter to JVDI readership

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October 31, 2014 at 11:22PM The genotyping of Infectious bronchitis virus in Taiwan by a multiplex amplification refractory mutation system reverse transcription polymerase chain reaction

Infectious bronchitis virus (IBV; Avian coronavirus) causes acute respiratory and reproductive and urogenital diseases in chickens. Following sequence alignment of IBV strains, a combination of selective primer sets was designed to individually amplify the IBV wild-type and vaccine strains using a multiplex amplification refractory mutation system reverse transcription polymerase chain reaction (ARMS RT-PCR) approach. This system was shown to discriminate the IBV wild-type and vaccine strains. Moreover, an ARMS real-time RT-PCR (ARMS qRT-PCR) was combined with a high-resolution analysis (HRMA) to establish a melt curve analysis program. The specificity of the ARMS RT-PCR and the ARMS qRT-PCR was verified using unrelated avian viruses. Different melting temperatures and distinct normalized and shifted melting curve patterns for the IBV Mass, IBV H120, IBV TW-I, and IBV TW-II strains were detected. The new assays were used on samples of lung and trachea as well as virus from allantoic fluid and cell culture. In addition to being able to detect the presence of IBV vaccine and wild-type strains by ARMS RT-PCR, the IBV Mass, IBV H120, IBV TW-I, and IBV TW-II strains were distinguished using ARMS qRT-PCR by their melting temperatures and by HRMA. These approaches have acceptable sensitivities and specificities and therefore should be able to serve as options when carrying out differential diagnosis of IBV in Taiwan and China.

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October 31, 2014 at 11:22PM Interlaboratory and between-specimen comparisons of diagnostic tests for leptospirosis in sheep and cattle

A study was performed to investigate interlaboratory test agreement between a research and a commercial veterinary diagnostic laboratory on blood and urine samples, and to investigate test agreement between blood, urine, and kidney samples (research laboratory) for leptospirosis diagnosis. Samples were sourced from 399 sheep and 146 beef cattle from a local abattoir. Interlaboratory agreement for real-time quantitative polymerase chain reaction (qPCR) results on urine samples was almost perfect (kappa = 0.90), despite the use of different amplification targets (DNA gyrase subunit B gene vs. 16s ribosomal RNA gene), chemistries (SYTO9 vs. TaqMan probe), and pre-PCR processing. Interlaboratory agreement for microscopic agglutination test (MAT) positivity was almost perfect (kappa = 0.93) for Leptospira borgpetersenii serovar Hardjo subtype Hardjobovis (Hardjobovis) but moderate (kappa = 0.53) for Leptospira interrogans serovar Pomona (Pomona). Among animals that had different titers recorded, higher Hardjobovis and lower Pomona titers were reported by the commercial laboratory than by the research laboratory (P < 0.005). These interlaboratory comparisons can assist researchers and diagnosticians in interpreting the sometimes discrepant test results. Within the research laboratory, the comparison of qPCR results on urine and kidney showed almost perfect agreement (kappa = 0.84), suggesting that the qPCR on these 2 specimens can be used interchangeably. The agreement between MAT positivity and urine and kidney qPCR results was fair (kappa = 0.32 and kappa = 0.33, respectively). However, the prevalence ratio of urine and kidney qPCR positivity in Hardjobovis-seropositive versus Hardjobovis-seronegative sheep indicated that Hardjobovis seropositivity found in sheep may be able to predict shedding or renal carriage.

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October 31, 2014 at 11:22PM Retrospective study of central nervous system lesions and association with Parelaphostrongylus species by histology and specific nested polymerase chain reaction in domestic camelids and wild ungulates

Formalin-fixed, paraffin-embedded tissues from elk (Cervus elaphus), goats, and camelids with case histories and lesions suggestive of Parelaphostrongylus tenuis were examined by histology to characterize lesions that could aid in definitively diagnosing P. tenuis infection. Additionally, sections of paraffin-embedded tissue were used in a nested polymerase chain reaction (nPCR) using Parelaphostrongylus-specific primers to determine how PCR results corresponded with histological findings. Histological changes in brain and spinal cord consisted of linear tracks of hemorrhage; tracks or perivascular accumulations of hemosiderin-laden macrophages; acute foci of axonal degeneration and/or linear glial scars; and perivascular, parenchymal, or meningeal accumulations of eosinophils and/or lymphocytes and plasma cells. Of the 43 samples with histologic lesions consistent with neural larval migrans, 19 were PCR positive; however, only 8 were confirmed Parelaphostrongylus by DNA sequencing. Additionally, 1 goat was identified with a protostrongylid that had a 97% identity to both Parelaphostrongylus odocoilei and a protostrongylid nematode from pampas deer (Ozotoceros bezoarticus celer) from Argentina. None of the histologic lesions individually or in combination correlated statistically to positive molecular tests for the nematode. The results indicate that it is possible to extract Parelaphostrongylus DNA from formalin-fixed, paraffin-embedded tissue, but extended fixation presumably can cause DNA crosslinking. Nested PCR provides another diagnostic tool to identify the cause of neurologic disease in camelids and elk with histologic lesions consistent with neural larval migrans. Furthermore, potential novel protostrongylid DNA was detected from a goat with lesions consistent with P. tenuis infection, suggesting that other neurotropic Parelaphostrongylus species may occur locally.

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October 31, 2014 at 11:22PM Field evaluation of a quantitative polymerase chain reaction assay for Mycoplasma hyorhinis

Mycoplasma hyorhinis has emerged as an important cause of systemic disease in nursery pigs. However, this bacterium can also be found in the upper respiratory tract of healthy swine. The current study describes the development of a quantitative polymerase chain reaction assay for the detection of M. hyorhinis and the evaluation of the assay in both disease diagnosis and disease surveillance using a large number of field samples. The analytical sensitivity was estimated to be 12 genome equivalents/μl. The assay was highly specific, detecting all 25 M. hyorhinis isolates tested and none of the 19 nontarget species tested. Assay repeatability was evaluated by testing different matrices spiked with known amounts of M. hyorhinis. Overall, assessment of the repeatability of the assay showed suitable precision within and between runs for all matrices. The coefficient of variation ranged from 10% to 24%. Mycoplasma hyorhinis DNA was detected in 48% of samples (pericardium, pleura, joints, nasal cavity, and lungs) from pigs with systemic disease. Mycoplasma hyorhinis was detected in nasal (92%) and oropharyngeal swabs (66%), as well as in oral fluids (100%). Potential uses of this tool involve the characterization of the prevalence of this pathogen in swine herds as well as bacterial quantification to evaluate intervention efficacy.

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October 31, 2014 at 11:22PM Moraxella spp. isolated from field outbreaks of infectious bovine keratoconjunctivitis: a retrospective study of case submissions from 2010 to 2013

Infectious bovine keratoconjunctivitis (IBK), also known as pinkeye, is the most costly eye disease of cattle. The principal etiologic agent of IBK is the Gram-negative bacterium Moraxella bovis. However, there have been reports of IBK outbreaks associated with Moraxella bovoculi. A retrospective study of IBK diagnostic cases submitted from July 1, 2010 through October 31, 2013 was conducted. Included in the study were 1,042 Moraxella isolates from 1,538 swabs of lacrimal secretions collected from 282 herds from 30 U.S. states. Moraxella isolates were identified to the species level and were composed of M. bovoculi (701 isolates), M. bovis (295 isolates), Moraxella ovis (5 isolates), and other Moraxella spp. (41). Minimum inhibitory concentrations required for 90% growth inhibition (MIC₉₀) was calculated for representative isolates. The MIC₉₀ values for both M. bovis and M. bovoculi were as follows: ampicillin and ceftiofur: ≤0.25 µg/ml; clindamycin: 2 µg/ml; danofloxacin and enrofloxacin: ≤0.12 µg/ml; florfenicol: 0.5 µg/ml; gentamicin: 1 µg/ml; neomycin: 4 µg/ml; tulathromycin: 2 µg/ml; and tylosin: 8 µg/ml. The MIC₉₀ values for M. bovoculi included the following: chlortetracycline: ≤0.5 µg/ml; oxytetracycline: 4 µg/ml; penicillin: 0.25 µg/ml; spectinomycin: 32 µg/ml; sulfadimethoxine: >256 µg/ml; tiamulin: 1 µg/ml; and trimethoprim–sulfamethoxazole: 4 µg/ml. For M. bovis, MIC₉₀ values included the following: chlortetracycline and oxytetracycline: 1 µg/ml; penicillin: ≤0.12 µg/ml; spectinomycin: 16 µg/ml; sulfadimethoxine: ≤256 µg/ml; tiamulin: ≤0.5 µg/ml; and trimethoprim–sulfamethoxazole: ≤2 µg/ml. The current work describes the frequency of isolation and differences in antimicrobial sensitivity observed among Moraxella isolates from case submissions.

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October 31, 2014 at 11:22PM Impact of antigenic diversity on laboratory diagnosis of Avian bornavirus infections in birds

Avian bornaviruses (ABVs) are a group of genetically diverse viruses within the Bornaviridae family that can infect numerous avian species and represent the causative agents of proventricular dilatation disease, an often fatal disease that is widely distributed in captive populations of parrots and related species. The current study was designed to assess the antigenic variability of the family Bornaviridae and to determine its impact on ABV diagnosis by employing fluorescent antibody assays. It was shown that polyclonal rabbit sera directed against recombinant bornavirus nucleoprotein, X protein, phosphoprotein, and matrix protein provided sufficient cross-reactivity for the detection of viral antigen from a broad range of bornavirus genotypes grown in cell culture. In contrast, a rabbit anti-glycoprotein serum and 2 monoclonal antibodies directed against nucleoprotein and phosphoprotein proteins reacted more specifically. Antibodies were readily detected in sera from avian patients infected with known ABV genotypes if cells persistently infected with a variety of different bornavirus genotypes were used for analysis. For all sera, calculated antibody titers were highest when the homologous or a closely related target virus was used for the assay. Cross-reactivity with more distantly related genotypes of other phylogenetic groups was usually reduced, resulting in titer reduction of up to 3 log units. The presented results contribute to a better understanding of the antigenic diversity of family Bornaviridae and further emphasize the importance of choosing appropriate diagnostic tools for sensitive detection of ABV infections.

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October 31, 2014 at 11:22PM Serological diagnosis of Besnoitia bennetti infection in donkeys (Equus asinus)

Besnoitiosis is an emerging infectious disease of donkeys (Equus asinus) in the United States for which there are currently no serologic methods of diagnosis. A study was performed to evaluate physical examination findings and 3 serologic assays for the detection of Besnoitia bennetti infection in donkeys. A prospective study of 416 donkeys from 6 privately owned herds across 5 U.S. states (New York, Pennsylvania, Vermont, Oregon, and Washington) was performed. Donkeys were examined for clinical lesions suggestive of besnoitiosis and evaluated for antibodies against B. bennetti using a fluorescent antibody test (FAT) and 2 immunoblot assays specific for bradyzoite and tachyzoite antigens, respectively. Donkeys were confirmed to be infected with B. bennetti by histology (cases; n = 32) and were compared to those with no clinical signs of besnoitiosis (controls; n = 384). Identifying clinical lesions in 2 or more locations correctly identified infected donkeys 83% of the time. Donkeys with besnoitiosis had significantly higher FAT titers (P < 0.001) and numbers of bradyzoite (P < 0.001) and tachyzoite (P < 0.001) immunoblot bands than control donkeys. The sensitivity and specificity of the serologic assays for detecting besnoitiosis was 88% and 96% for FAT, 81% and 91% for bradyzoite immunoblot, and 91% and 92% for tachyzoite immunoblot, respectively. Fluorescent antibody and immunoblot assays are effective at identifying donkeys with besnoitiosis and provide a more efficient and less invasive diagnostic alternative to histology.

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October 31, 2014 at 11:22PM Comparison of serum, ear notches, and nasal and saliva swabs for Bovine viral diarrhea virus antigen detection in colostrum-fed persistently infected (PI) calves and non-PI calves

The diagnosis of neonatal and young calves persistently infected (PI) with Bovine viral diarrhea virus (BVDV) by antigen-capture enzyme-linked immunosorbent assay (ACE) may be complicated by interference from colostrum-derived specific antibodies. Ten calves, with 3 calves identified as PI and 7 as non-PI were used in the current study. All non-PI calves were shown to be seropositive for BVDV-specific antibodies by antibody enzyme-linked immunosorbent assay (Ab-ELISA) on serum. Serum samples, ear notch samples, and nasal and saliva swabs were collected from each calf from birth until 12 weeks of age and tested by ELISA for BVDV-specific antigen and antibodies. Following colostrum ingestion, Ab-ELISA sample-to-positive (S/P) ratios rose by a mean of 0.95 (95% confidence interval [CI] = 0.64–1.25) and 1.72 (95% CI = 1.55–1.89) in seropositive, non-PI calves and in PI calves, respectively. The mean S/P ratios then declined to approximately 1.1 in non-PI calves and 0.5 in PI calves at between 60 and 80 days of age. In PI calves, testing for antigen in serum and nasal and saliva swabs was subject to interference by colostrum-derived antibodies in calves up to 3 weeks of age. Nasal swabs were less affected than serum and saliva swabs. Ear notches maintained positive ACE corrected optical densities at all sample times, despite a drop in the signal following the ingestion of colostrum.

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October 31, 2014 at 11:22PM Outbreaks of Vesicular stomatitis Alagoas virus in horses and cattle in northeastern Brazil

The current article describes outbreaks of vesicular stomatitis (VS) in horses and cattle in Paraiba and Rio Grande do Norte states, northeastern Brazil, between June and August 2013. The reported cases affected 15–20 horses and 6 cattle distributed over 6 small farms in 4 municipalities, but additional data indicated the involvement of a large number of animals on several farms. The disease was characterized by blisters; eruptive lesions in coronary bands, lips, mouth, and muzzle; salivation; claudication and loss of condition. Swollen lower limbs and lips, and ulcerated and erosive areas in the lips and muzzle were observed in some horses. A necrotizing vesiculopustular dermatitis and stomatitis was observed histologically. Vesicular stomatitis virus was isolated from the vesicular fluid of a horse lesion and shown to be serologically related to the VS Indiana serogroup (VSIV) by virus neutralization. Convalescent sera of affected horses and cattle, and from healthy contacts, harbored high levels of neutralizing antibodies against the isolated virus (named VSIV-3 2013SaoBento/ParaibaE). Genomic sequences of VSIV subtype 3 (Vesicular stomatitis Alagoas virus) were amplified by reverse transcription polymerase chain reaction out of clinical specimens from a cow and a horse from different farms. Nucleotide sequencing and phylogenetic analysis of the phosphoprotein gene indicated that the 2 isolates were derived from the same virus and clustered them in VSIV-3, along with VS viruses identified in southeastern and northeastern Brazil in the last decades. Thus, the present report demonstrates the circulation of VSIV-3 in northeastern Brazil and urges for more effective diagnosis and surveillance.

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October 31, 2014 at 11:22PM Isolation of Aureimonas altamirensis, a Brucella canis-like bacterium, from an edematous canine testicle

Microbiological and histological analysis of a sample from a swollen testicle of a 2-year-old Border Collie dog revealed a mixed infection of the fungus Blastomyces dermatitidis and the Gram-negative bacterium Aureimonas altamirensis. When subjected to an automated microbial identification system, the latter isolate was provisionally identified as Psychrobacter phenylpyruvicus, but the organism shared several biochemical features with Brucella canis and exhibited agglutination, albeit weakly, with anti–B. canis antiserum. Unequivocal identification of the organism was only achieved by 16S ribosomal RNA gene sequencing, ultimately establishing the identity as A. altamirensis. Since its first description in 2006, this organism has been isolated infrequently from human clinical samples, but, to the authors’ knowledge, has not been reported from a veterinary clinical sample. While of unknown clinical significance with respect to the pathology observed for the polymicrobial infection described herein, it highlights the critical importance to unambiguously identify the microbe for diagnostic, epidemiological, infection control, and public health purposes.

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October 31, 2014 at 11:22PM Diagnostic features in 10 naturally occurring cases of acute fatal canine leptospirosis

The current report describes the diagnostic features in 10 cases of acute fatal canine leptospirosis with minimal renal and hepatic changes that may present a diagnostic challenge for the pathologist. Most affected dogs were less than 6 months of age and had a biochemical profile consistent with hepatorenal dysfunction. Clinical signs consisted of vomiting, depression, icterus, dehydration, diarrhea, and anorexia. All dogs died or were humanely euthanized within 3–7 days after the onset of clinical disease. Necropsy findings included pulmonary edema with hemorrhages, icterus, renal and hepatic pallor and swelling, and gastric edema with hemorrhage. Despite severe azotemia, histological changes in the kidneys were subtle in all dogs, and included mild renal tubular simplification, with single-cell necrosis and attenuation, along with minimal interstitial lymphoplasmacytic inflammation, edema, and hemorrhage. Hepatic lesions included scattered hepatocellular single-cell necrosis and hepatocellular dissociation. Prominent extrarenal lesions typically associated with uremia including vascular fibrinoid necrosis in multiple organs, pulmonary mineralization with occasional fibrinosuppurative exudation, and gastric mineralization were also present. Postmortem diagnostic confirmation was based on the detection of leptospiral antigen on fresh renal samples by fluorescent antibody test and on the demonstration of intact spirochetes in sections of kidneys using immunohistochemical staining. Acute fatal canine leptospirosis occurred as a fulminant hepatorenal disease affecting mainly young dogs, and the diagnosis was dependent on the recognition of the subtle renal changes with confirmation via fluorescent antibody testing or immunohistochemical staining.

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October 31, 2014 at 11:22PM Vascular hamartoma in the central nervous system of a foal

Vascular hamartomas are non-neoplastic developmental anomalies of vessels. Cases of cerebral vascular hamartomas have been previously reported in dogs and cats. A 4-week-old Freiberger foal had shown persistent problems with breathing and swallowing since birth, and bilateral laryngeal paralysis was diagnosed. The foal subsequently developed left sided facial nerve paralysis and a secondary corneal ulcer in the left eye. Necropsy revealed a pinkish mass in the obex region of the brain. The mass was further investigated by histology and immunohistochemistry. Histologically, the mass consisted of many thin-walled, blood-filled vascular structures of variable diameter involving the white matter of the obex. The lining cells were immunohistochemically positive for factor VIII (von Willebrand factor) interpreted as endothelial cells. The endothelial lining showed also variable immunoreactivity for smooth muscle actin and vimentin. Normal neural parenchyma labeled with antibodies directed against glial fibrillary acidic protein and neuron-specific enolase was present between the vascular proliferations. A diagnosis of focal vascular hamartoma in the obex was made. The development of clinical signs is attributed to the compression of the surrounding neural parenchyma.

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October 31, 2014 at 11:22PM Hyperplastic goiter in two adult dairy cows

Iodine excess and resultant hyperplastic goiter are well documented in neonatal ruminants, but little is reported on iodine excess in adult ruminants and associated histological changes of the thyroid gland. Two adult Holstein cows from a Michigan dairy herd that had lost several other animals had nonspecific clinical signs of illness and were submitted for necropsy. Thyroid glands of one of these 2 animals were grossly and markedly enlarged, and histologically, thyroid glands from both animals had regions of cystic nodular hyperplasia and follicular atrophy. Thyroid glands from both animals had markedly elevated iodine concentrations. Investigation into the potential source of excessive iodine on the farm revealed multiple sources of supplemental dietary iodine and probable uneven feed and mineral mixing. Based on the findings of this investigation, adult cattle could be susceptible to excessive doses of iodine. Possibility of previous iodine deficiency before supplementation period, with subsequent development and persistence of thyroid hyperplasia and cystic change, cannot be completely excluded. Current findings suggested that iodine excess in adult cattle can result in nodular hyperplastic goiter. Use of iodized salt in mineral supplements in adult dairy herds is common practice, and accidental excessive iodine supplement may be more common than reported. Recognizing gross and histological thyroid gland changes, consisting of concurrent cystic follicular hyperplasia, atrophy, and fibrosis should raise suspicion of iodine excess and/or prior deficiency in a cattle herd, and ancillary tests such as serum iodine measurements should be part of the diagnostic workup in suspected cases.

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October 31, 2014 at 11:22PM Spirocerca lupi granulomatous pneumonia in two free-ranging maned wolves (Chrysocyon brachyurus) from central Brazil

The current report describes granulomatous pneumonia due to Spirocerca lupi in 2 free-ranging maned wolves (Chrysocyon brachyurus). Both wolves had multiple, white, 1–1.5 cm in diameter, soft, encapsulated granulomas in the caudal lung lobes, which contained centrally placed parasites on cut sections. Microscopically, there was granulomatous inflammation with numerous intralesional sections of spirurid nematodes. Representative complete adult specimens of nematodes derived from these lesions were submitted for parasitological exam and identified as the spirurid S. lupi. To the authors’ knowledge, there have been no published reports of S. lupi in maned wolves.

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October 31, 2014 at 11:22PM Abortion in cattle due to infection with Staphylococcus lugdunensis

An aborted fetus of 7 months gestation, the associated placenta, and a single blood sample from the dam were submitted for diagnostic investigation to the diagnostic laboratory of the Lombardy and Emilia-Romagna Experimental Zooprophylactic Institute in Parma, Italy. The serum was negative for Neospora caninum, Coxiella burnetii, Chlamydophila abortus, Bovine herpesvirus 1 (BHV-1), Bovine viral diarrhea virus (BVDV), Brucella abortus, and Brucella melitensis. Fetal tissues and placental cotyledons were pooled and tested by polymerase chain reaction (PCR) for the presence of BHV-1, Bovine herpesvirus 4, BVDV, N. caninum, C. burnetii, Chlamydophila spp., Schmallemberg virus, and Leptospira interrogans. All PCR assays were negative. Bacteriological examinations performed on the fetal organs revealed a pure growth of Staphylococcus lugdunensis in all organs cultured. In human beings, S. lugdunensis is responsible for community-acquired and nosocomial infections, in both immunocompetent and immunocompromised patients. In veterinary medicine, the pathogenic potential of S. lugdunensis has not been fully investigated. The incidence of S. lugdunensis is regarded as being underreported because it could be easily misidentified as Staphylococcus aureus. The current report documents the ability of S. lugdunensis to cause abortion in cattle, indicating the need for accurate diagnostic procedures to identify this emerging and zoonotic pathogen whose incidence is likely underestimated in both human and veterinary medicine.

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October 31, 2014 at 11:22PM Oxidant-induced damage to equine erythrocytes from exposure to Pistacia atlantica, Pistacia terebinthus, and Pistacia chinensis

Two horses were referred for methemoglobinemia and hemolytic anemia following 5 acute deaths in their herd from an unidentified toxin source. Horses have a greater risk than other mammalian species of developing methemoglobinemia and hemolytic anemia following ingestion of oxidizing toxins, due to deficiencies in the mechanisms that protect against oxidative damage in erythrocytes. Their susceptibility to oxidative erythrocyte damage is evident in the numerous cases of red maple (Acer rubrum) toxicosis. The suspected toxins causing A. rubrum toxicosis are tannic acid, gallic acid, and a metabolite of gallic acid, pyrogallol. These compounds can be found in a variety of plants, posing a risk to equine health. In order to quickly identify toxin sources, 2 rapid in vitro assays were developed to screen plant extracts for the ability to induce methemoglobin formation or cause hemolysis in healthy equine donor erythrocytes. The plant extract screening focused on 3 species of the genus Pistacia: P. atlantica, P. terebinthus, and P. chinensis, which were located in the horse pasture. Extracts of the seeds and leaves of each species induced methemoglobin formation and resulted in hemolysis, with seed extracts having greater potency. The in vitro assays used in the current study provide a useful diagnostic method for the rapid identification of oxidizing agents from unidentified sources. There is no effective treatment for oxidative erythrocyte damage in horses, making rapid identification and removal of the source essential for the prevention of poisoning.

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October 31, 2014 at 11:22PM Cholecystic adenocarcinoma and pancreatic insulinomas in a goat

A 13-year-old female Boer goat with a history of chronic arthritis and recurrent episodes of recumbency, increased serum gamma-glutamyl transferase, and complete inability to stand was submitted for necropsy. Gross changes included the presence of a white, firm, smooth, 6 cm x 4 cm x 3 cm mass that diffusely expanded and partially effaced the gall bladder and infiltrated the adjacent hepatic parenchyma. On cut surface, the mass was pale yellow and had small, irregular, dark yellow areas. Scattered through the pancreas were 2 gray, well-demarcated, soft, homogeneous, 1 cm in diameter nodules that bulged out from the capsular surface. The right femoral head had a locally extensive area of cartilage erosion. Histological and immunohistochemical evaluation of the gall bladder and pancreatic nodules revealed a primary cholecystic adenocarcinoma and multifocal insulinomas, respectively. A metastatic focus from the gall bladder neoplasm was observed infiltrating the right adrenal gland medulla. The goat also had mild pulmonary infestation by Muellerius capillaris. Primary hepatobiliary and pancreatic neoplasia is rare in goats, and to the authors’ knowledge, neither cholecystic adenocarcinoma nor pancreatic insulinomas have been previously reported in this species.

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October 31, 2014 at 11:22PM Flavobacterium columnare: an important contributing factor to fish die-offs in southern lakes of Saskatchewan, Canada

During June and July 2012, Buffalo Pound Lake and Blackstrap Lake in Saskatchewan, Canada were visited biweekly and surveyed for sick and dying fish. During this investigation, 2 fish kills were identified. Buffalo Pound experienced a large die-off of yellow perch (Perca flavascens) in June, while Blackstrap experienced a die-off of lake whitefish (Coregonus clupeaformis) in July. In excess of 50 fish were examined for gross lesions at each lake, and dead and moribund fish consistently had 1 or more of the following lesions: multifocal petechial cutaneous hemorrhage, skin ulceration, or branchial necrosis. Of these, 17 fish were collected for necropsy, and major tissues were submitted for histology. Aerobic bacterial culture was performed on 16 out of 17 fish. In 7 out of 8 (88%) yellow perch, the body wall had multiple areas of pale discoloration that corresponded to erosion and ulceration of the skin. Seven out of 8 (88%) whitefish had severe necrotizing branchiitis, and 8 out of 8 (100%) had severe epicardial parasitism, consistent with Ichthyocotylurus erraticus. Wet mounts of skin and gill lesions demonstrated filamentous bacteria with gliding motility, which often formed haystack-like arrangements. Flavobacterium columnare and Aeromonas hydrophila were cultured from skin and gill lesions of all fish. Based on the characteristic appearance and distribution of lesions, mortality was attributed to columnaris disease with secondary infection with A. hydrophila. The current study demonstrates that columnaris disease is an important contributor to fish kills in southern Saskatchewan lakes. However, further research is needed to determine what role environmental factors play in outbreaks of columnaris disease in prairie lakes.

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October 31, 2014 at 12:00PM FDA Pharmacists Help Consumers Use Medicines Safely

Got a question about a medicine? FDA's Division of Drug Information can answer it.



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Federal Government Conducts Clinical Trials Of Ebola Vaccine And Approves More Diagnostics

Agencies push advances to fight, detect deadly disease



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October 29, 2014 at 01:23PM Clinical Investigator Status (Biologics)

Clinical Investigator Inspection List updated through 3/11/2010.



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Compound Reverses The Anticlotting Effects Of Heparin


Translational Medicine: Antidote shuts down anticoagulation of all clinically available heparins



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October 30, 2014 at 04:22PM Symposium sur le buffle d’Afrique

Coorganisé par le Cirad

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October 30, 2014 at 03:59PM October 29, 2014 Approval Letter - TRUMENBA

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October 29, 2014 at 07:09PM Resisting Resistance: FDA’s Antiparasitic Resistance Management Strategy - A Webinar

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Transgenic Plants Sop Up Soil Pollutants

Environment: Plants bearing bacterial genes metabolize toxic organic compounds in soil



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October 29, 2014 at 01:29PM List of Establishments Granted Approval for a Variance to 21CFR640.3(d) and 21CFR640.3(f)

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October 29, 2014 at 01:00PM Mammography: What You Need to Know

Mammograms are still the best tool for breast cancer screening. As we observe Breast Cancer Awareness Month this October, learn how FDA certifies facilities that perform mammography�and, clears and approves mammography devices�to help keep you safe.



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October 28, 2014 at 03:00PM Generic Drugs Undergo Rigorous FDA Scrutiny

How does FDA ensure that generic prescription drugs are safe and effective alternatives to brand-name drugs? The generic drugs approval process includes a review of scientific data on manufacturing, ingredients and performance. Plus, FDA tests selected drugs, both brand-name and generic, in its laboratories.



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October 27, 2014 at 07:50PM Shur-Green Farms Issues Voluntary Nationwide Recall of Lascadoil/Soyoil Due to Possible Lasalocid Contamination

Shur-Green Farms LLC(Ansonia, OH) has voluntarily recalled loads of Soyoil containing Lascadoil, industrial processing waste oil, which was intended for non-food product or bio-fuels but may have been used as a feed ingredient. This voluntary recall is the result of death in turkeys.



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October 27, 2014 at 07:19PM Flebogamma DIF 5%

Updated Package Insert, December 2009.



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October 27, 2014 at 03:50PM Z Natural Foods Recalls Lightly Roasted Organic Carob Powder Due to Possible Salmonella Health Risk

Z Natural Foods of West Palm Beach, Florida is recalling 55 lbs of Lightly Roasted Organic Carob Powder because it has the potential to be contaminated with Salmonella, an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems. Healthy persons infected with Salmonella often experience fever, diarrhea (which may be bloody), nausea, vomiting and abdominal pain.



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October 27, 2014 at 02:50PM Congrès AFTER 2014 : favoriser l’accès au marché des produits traditionnels africains

Le premier congrès du projet AFTER (African Food Tradition rEvisited by Research) se déroulera à Dakar (Sénégal), du 11 au 12 novembre 2014 sur le thème «Valorisation des aliments traditionnels africains : innovations, qualité et accès au marché ».

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October 27, 2014 at 12:42PM Mixing Medications and Dietary Supplements Can Endanger Your Health

Is mixing medicines and dietary supplements a good idea? Find out how using them together can endanger your health and why it's important to discuss them with your health care professional.



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Building DNA Crystals Brick-By-Brick

Researchers program short DNA strands to form microscopic crystals



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Climbing Fern’s Sex Chemistry Exposed

Hormone signaling interplay between early and late bloomers determines plant’s gender



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Radiolabeled Sweetener Helps Image Bacterial Infections In Mice


Positron emission tomography tracer based on sorbitol detects gram-negative infections



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White House Halts Gain-Of-Function Research

Recent biosecurity failures prompt a hiatus and review of the controversial research subject



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Mining Venoms

Understanding the composition of venoms can yield insight into evolution and provide new inspiration for drugs



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Mining Venoms

Understanding the composition of venoms can yield insight into evolution and provide new inspiration for drugs



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October 25, 2014 at 02:29AM Lundberg Family Farms Recalls Sea Salt Rice Chips Due to Undeclared Allergen

Lundberg Family Farms announced that it is voluntarily recalling from distribution in the United States and Canada, specific bags of Sea Salt Rice Chips due to possible presence of an undeclared dairy allergen. The issue was discovered through a consumer complaint.



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October 24, 2014 at 10:54PM Rome Packing Co., Inc. Recalls Fresh And Frozen Crab Meat Because Of Possible Health Risk

Rome Packing Co., Inc. has issued a voluntary recall of Ocean’s Catch brand All Natural Jonah Crab Leg Meat after routine product sampling by the company determined some of the finished products may have been contaminated with Listeria monocytogenes bacteria. Listeria monocytogenes, is an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems.



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October 24, 2014 at 04:42PM Draft Guidance for Industry-Providing Submissions in Electronic Format — Postmarketing Safety Reports for Vaccines

via What's New: Vaccines, Blood & Biologics RSS Feed http://ift.tt/1wDUaC1

October 23, 2014 at 05:19PM Palms of controversies - Oil palm and development challenges

Initialement publié en français, l'ouvrage La palme des controverses est désormais disponible en anglais sous le titre Palms of controversies et téléchargeable gratuitement en ligne. Cet ouvrage présente l’ensemble de la filière de production et de transformation de l’huile de palme, depuis la culture du palmier à huile jusqu’à l’utilisation de l’huile de palme dans des produits courants. L’ouvrage vise à apporter des informations globales et équilibrées sur un sujet très controversé dans les médias et la perception du grand public.

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October 23, 2014 at 04:22PM Élaborer et mettre en œuvre une stratégie d’information

Après la version anglaise, le cours numérique Imark sur l’élaboration et la mise en œuvre d’une stratégie d’information est désormais également disponible en français.

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Iridium Dressed To The Nines

Periodic Table: IrO₄⁺ is the first molecule with an element in the +9 oxidation state



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Troublemaking HER3 Enzyme Trashed

Drug Discovery: Cancer-causing pseudokinase directed to cellular garbage can



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October 23, 2014 at 01:45PM Finding Food Allergens Where They Shouldn't Be

Undeclared allergens are the leading cause of food recalls by the FDA. Which foods are most often affected, and which allergens are involved?



via FDA Consumer Health Information Updates http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm416577.htm

October 23, 2014 at 12:05PM Políticas públicas y agriculturas familiares en América Latina y el Caribe : balance, desafíos y perspectivas

L’ouvrage Políticas públicas y agriculturas familiares en América Latina y el Caribe : balance, desafíos y perspectivas présente la diversité des agricultures familiales en Amérique latine ainsi que celle des politiques publiques qui lui sont dédiées. Il rassemble les résultats d’une étude menée le Cirad et vingt partenaires latino-américains. Il constitue un des socles des débats organisés dans le cadre du séminaire international Politicas publicas y agricultura familiar en América Latine y el Caribe qui se tient du 2 au 5 novembre 2014 à Santiago du Chili.

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October 23, 2014 at 11:58AM Mieux valoriser les agricultures familiales en Amérique latine

L’agriculture familiale en Amérique latine sera au centre de l’attention des décideurs et spécialistes des politiques publiques du 2 au 5 novembre 2014 à Santiago du Chili. Le Cirad, la Cepal, la FAO, le FIDA, le ministère de l’Agriculture du Chili et l’IICA y organisent, dans le cadre de l’année internationale de l’agriculture familiale, le séminaire international Políticas públicas y agricultura familiar en América Latina y el Caribe.

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October 23, 2014 at 10:54AM Draft Guidance for Industry: Same Surgical Procedure Exception under 21 CFR 1271.15(b): Questions and Answers Regarding the Scope of the Exception

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Peeking At A Cell’s Small Molecules

Mass spectrometry method can analyze an individual living cell’s metabolites and lipids in minutes



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Peeking At A Cell’s Small Molecules

Mass spectrometry method can analyze an individual living cell’s metabolites and lipids in minutes



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October 22, 2014 at 06:20PM Bailey Farms Inc. Recalls Fresh Serrano Chile Peppers Because Of Possible Health Risk

Bailey Farms, Inc. of Oxford, NC is voluntarily recalling 6,215 pounds of Fresh Serrano Chile Peppers, because it has the potential to be contaminated with Salmonella, an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems. Healthy persons infected with Salmonella often experience fever, diarrhea (which may be bloody), nausea, vomiting and abdominal pain. In rare circumstances, infection with Salmonella can result in the organism getting into the bloodstream and producing more severe illnesses such as arterial infections (i.e., infected aneurysms), endocarditic and arthritis.



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October 22, 2014 at 04:47PM Food Safety Modernization Act and Animal Feed

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October 22, 2014 at 02:12PM Adenovirus Type 4 and Type 7 Vaccine, Live, Oral

via What's New: Vaccines, Blood & Biologics RSS Feed http://ift.tt/1ykpXdF

October 21, 2014 at 12:18PM On the web: the Vanuatu herbarium

9000 spécimens de près de 1000 espèces, 700 photos descriptives, des cartes… Découvrez la diversité végétale de l’archipel du Vanuatu sur le site internet de l’herbier du Vanuatu.

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October 17, 2014 at 03:32PM Knowledge legitimization, the keystone of participatory research

Participatory approaches are currently fashionable. However, if they involve research, things are not always self-evident, particularly if knowledge of many origins is at stake. In a study of participatory research, an anthropologist and a specialist in information and communication sciences looked at the ways in which knowledge was legitimized within a project in Senegal.

How can scientific knowledge be legitimized? Within this project, two local players, a farmers' association leader and a marabout, were involved. The marabout, for instance, translated the issues at stake by making public reference to surahs from the Koran. However, legitimization must also apply to local knowledge, from the point of view of scientists. In this case too, novel techniques were developed. The use of photos by the various players, combined with surveys, served to reveal and set out the viewpoints of each stakeholder.

The study also showed that the legitimization process led to a change in the stakeholders' social status: the smallholders' leader now describes himself as a "peasant microbiologist", while the marabout boosted his religious knowledge by translating the scientific knowledge. Lastly, from the researchers' point of view, a clear distinction can be made between two concepts of research: international production of advanced science within a highly competitive context, and the development of participatory science concerned with relevance and social issues.

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Mechanical Force May Help HIV Invade Cells

Cell Biology: T-cell receptors involved in the first step of HIV infection are sensitive to mechanical force in the lab



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October 21, 2014 at 12:18PM Sur le web : L’herbier du Vanuatu

9000 spécimens de près de 1000 espèces, 700 photos descriptives, des cartes… Découvrez la diversité végétale de l’archipel du Vanuatu sur le site internet de l’herbier du Vanuatu.

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Reductive Dehalogenase Structures Solved

Structural Biology: Enzymes use vitamin B12 in unusual way, could be tools for bioremediation of halogenated pollutants



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Pumpkin Spice Flavor

Popular lattes and treats contain no pumpkin, but boast plenty of food chemistry



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Charged Polymers Package Proteins

Drug Delivery: Researchers use oppositely charged polypeptides to create a protective sphere around proteins



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FBNCO—A Winning Combination In Elemental Bingo

Chemists have prepared a gas-phase molecule that is just a neon short of containing all the 2p-block elements



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Fluorinated Coating Repels Blood On Medical Devices

Combination of tethered and liquid perfluorocarbons wards off blood clotting without the need for anticoagulants



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Pills Simplify Fecal Transplants To Treat C. difficile Infections

Swallowing a capsule pits bacteria against bacteria in battle for gastrointestinal health



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Molecular Dynamics Results Challenge View Of How Potassium Ions Move Through Membrane-Spanning Channels

Simulations suggest that ions traverse cell-membrane pores without intervening water molecules



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October 18, 2014 at 05:34AM JFC International Inc. Issues Allergy Alert on Undeclared Milk in 'Hapi Pudding'

JFC International Inc. of Los Angeles, CA is voluntarily recalling all lot codes of its 3-pack Hapi Pudding with a net weight of 8.46 ounces (UPC 11152 13417), because they may contain undeclared milk. People who have allergies to milk run the risk of a serious or life-threatening allergic reaction if they consume the products.



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October 17, 2014 at 11:14PM AMS Health Sciences, LLC Issues Voluntary Recall of Saba Shark Cartilage Complex, 60 Capsule Bottles Due to Possible Salmonella Contamination

AMS Health Sciences, LLC is notifying the public that it is recalling 2014 bottles of Saba Shark Cartilage Complex due to possible contamination of Salmonella, an organism which can cause serious and sometimes fatal infections in young children frail or elderly people, and others with weakened immune systems. Healthy persons infected with Salmonella often experience fever, diarrhea (which may be bloody), nausea, vomiting and abdominal pain. In rare circumstances, infection with Salmonella can result in the organism getting into the bloodstream and producing more severe illnesses such as arterial infections (i.e., infected aneurysms), endocarditis and arthritis.



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October 17, 2014 at 10:45PM Oasis Brands, Inc. Recalls Products Lacteos Santa Martha Because of Possible Health Risk

Oasis Brands, Inc. of Miami, FL is recalling select lots of various Lacteos Santa Martha products with Best by dates of 07/01/14 through 12/31/14, because the products has the potential to be contaminated with Listeria monocytogenes, an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems. Although healthy individuals may suffer only short-term symptoms such as high fever, severe headache, stiffness, nausea, abdominal pain and diarrhea, Listeria infection can cause miscarriages and stillbirths among pregnant women.



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October 17, 2014 at 10:07PM United Natural Trading LLC dba/ Woodstock Farms Manufacturing Issues Allergy Alert for Undeclared Peanuts in Asian 7 Rice Cracker Mix

United Natural Trading LLC dba/ Woodstock Farms Manufacturing, Edison, New Jersey are recalling 22lb. bulk cases only (Lot# YOUI03) and Market Basket 12oz. tubs only (Lot# 14248) because they may contain undeclared peanuts. People who have allergies to peanuts run the risk of serious or life-threatening allergic reaction if they consume these products.



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October 17, 2014 at 09:51PM Publix Issues Voluntary Recall of Publix Asian Mix

Out of an abundance of caution, Publix Super Markets is issuing a voluntary recall for Publix Asian Mix because the product contains peanuts that are not declared on the packaging.



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October 17, 2014 at 08:45PM Resisting Resistance: FDA’s Antiparasitic Resistance Management Strategy - A Webinar

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October 17, 2014 at 05:22PM New Hope Mills Issues Allergy Alert on Undeclared Soy in New Hope Mills Gluten Free Chia Pancake and Waffle Mix

New Hope Mills Manufacturing of Auburn, NY is recalling all Gluten Free Chia Pancake and Waffle Mix because it may contain undeclared soy. People who have an allergy or severe sensitivity to soy run the risk of serious or life-threatening allergic reaction if they consume these products.



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Microbes Enrich Biogas And Synthesize Valuable Chemical

Renewable Energy: Researchers enlist bacteria to turn the carbon dioxide in raw biogas into succinic acid, leaving behind energy-rich methane



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October 17, 2014 at 03:32PM La légitimation des savoirs, pierre angulaire de la recherche participative

Les démarches participatives ont aujourd’hui le vent en poupe. Mais quand celles-ci intègrent la recherche, l’évidence n’est pas toujours de mise, notamment lorsque des savoirs d’origines multiples sont en jeu. Dans le cadre d’une étude consacrée à la recherche participative, une anthropologue et une spécialiste des sciences de l’information et de la communication ont observé les processus de légitimation des savoirs au sein d’un projet mené au Sénégal.

Comment légitimer les savoirs scientifiques ? Dans le contexte de ce projet, ce sont deux acteurs locaux, un leader associatif et un marabout qui y ont contribué. Ce dernier a, par exemple, traduit les enjeux du projet en se référant publiquement à des sourates du coran. Mais la légitimation doit aussi opérer pour les savoirs locaux, du point de vue des scientifiques. Là encore, des techniques originales ont été développées. L’utilisation de la photo par les différents acteurs, couplée à des enquêtes a permis de révéler et d’expliciter les regards de chacun.

L’étude montre également que le processus de légitimation conduit à une évolution des positions sociales des acteurs : le leader paysan se présente désormais comme un «microbiologiste paysan», le marabout a renforcé ses savoirs religieux au travers de sa traduction des savoirs scientifiques. Enfin, du point de vue des chercheurs, deux conceptions opposées de la recherche sont clairement à distinguer : une production scientifique internationale de pointe dans un contexte très compétitif et le développement d’une science participative, sensible à la pertinence et aux enjeux sociaux.

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October 17, 2014 at 02:57PM FDA Issues Draft Guidance with Recommendations for Drug Sponsors Submitting Two-Phased Chemistry, Manufacturing, and Controls Technical Data

The U.S. Food and Drug Administration issued today draft Guidance for Industry #227: Two-Phased Chemistry, Manufacturing, and Controls (CMC) Technical Sections, with recommendations for ways animal drug sponsors can submit chemistry, manufacturing, and controls (CMC) data to the agency to improve the efficiency of the New Animal Drug Application (NADA) review process.



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Preparedness For Ebola Questioned

Pharmaceuticals: U.S. is working to accelerate drug and vaccine clinical trials



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Naked Aryl Anion Made In Solution

Chemical Reactivity: Small, transient carbanion lacks traditional stabilizing factors



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Agilent To Exit NMR Business

Instrumentation: About 300 jobs will go as firm drops nuclear magnetic resonance operation



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Greener Synthetic Pathways AWARD

via Chemical & Engineering News: Biological SCENE http://ift.tt/1rAs8Ui

Cheerios-Fed Fungi Yield Biofilm Blockers

Natural Products: Soil fungi dine on breakfast cereal, then construct metabolites that block yeast biofilms



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October 16, 2014 at 02:00PM FDA Builds Closer Ties with Mexico

The Food and Drug Administration's Office of International Programs has offices around the world. Learn how the agency is working with Mexico.



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Broccoli Compound Improves Autism Symptoms

Natural products: Small study suggests antioxidant sulforaphane could be a drug target for treating the complex disorder



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October 15, 2014 at 01:30PM Research Flash: FDA Scientists Study Pediatric Brain Function

At FDA's National Center for Toxicological Research, investigators are researching pediatric brain function; and they've developed an innovative tool.



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October 14, 2014 at 04:58PM FDA's MedWatch Safety Alerts: September 2014

FDA warns consumers about the risk of lead poisoning from cold therapy, an updated drug alert on the lack of sterility assurance, and the recall of mole medication amidst safety concerns.



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October 14, 2014 at 05:42PM Biologics PREA Reviews and Labeling Changes

PREA Labeling Changes, Medical, Statistical, and Clinical Pharmacology Reviews of Pediatric Studies Conducted under Section 505B of the Federal Food, Drug, and Cosmetic Act (the Act), as amended by the FDA Amendments Act of 2007 (FDAAA). These assessments are for CBER regulated drugs approved under section 505 of the Act and biological drugs licensed under section 351 of the Public Health Service Act.



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Simple Molecules Block Bacterial Biofilms

Antimicrobials: Compounds thwart film formation by interrupting osmotic regulation in microbes



via Chemical & Engineering News: Biological SCENE http://ift.tt/1u0Tm8r

October 14, 2014 at 05:35PM FDA Helps Tackle Sickle Cell Disease

FDA is collaborating with patients, members of academia, and the pharmaceutical industry to encourage the development of new treatments for sickle cell disease (SCD).



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Chromatography Method Measures Protein-Small Molecule Interactions

Analytical Chemistry: Technique could be used to quickly assess drug candidates



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Chromatography Method Measures Protein-Small Molecule Interactions

Analytical Chemistry: Technique could be used to quickly assess drug candidates



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October 13, 2014 at 11:54AM Le Cirad au Salon du chocolat

Le Cirad participe à la vingtième édition du Salon du chocolat sous la bannière « A la recherche des cacaos du futur » -du 29 octobre au 2 novembre 2014 à Paris (Hall 5, Stand E22, Porte de Versailles).

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Microscopy Method Goes Deep

Atom-probe tomography reveals the 3-D positions of atoms inside hard-to-analyze materials



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Sponges Make Alkaloid Family With Mismatched Chirality

Unusual biosynthesis twist for sceptrin, ageliferin, and massadine may apply to other natural products



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Enhancing Bioreceptor Responsiveness

Researchers use biomolecular design technique to rationally engineer cooperative receptors



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Alumina Coating Tames Nanotube Toxicity

Mice show less lung damage after inhaling carbon nanotubes coated with aluminum oxide



via Chemical & Engineering News: Biological SCENE http://ift.tt/1qQnTnC

Manure From Antibiotic-Free Cows Promotes Antibiotic-Resistant Soil Bacteria

More research is needed to pinpoint the manure component that causes the effect



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Pain-Signaling Protein Activates T Cells Too

TRPV1, normally thought of as a sensory receptor, also regulates immune cells



via Chemical & Engineering News: Biological SCENE http://ift.tt/1qQnPo0

Ribozyme Swaps Genes With A Flip Of A Switch

Gene Therapy: Researchers developed a ribozyme that targets and replaces genes only in the presence of a specific small molecule, offering a more controlled approach to gene therapy



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October 10, 2014 at 06:08PM Biodiversité et services écosystémiques font bon ménage

Les zones identifiées comme importantes pour la biodiversité peuvent aussi l’être pour d’autres services écosystémiques comme le stockage du carbone, la conservation de l’eau et la qualité paysagère. Ce n’est pas forcément le cas des zones qui renferment de grandes quantités de carbone, qui, elles, fournissent des avantages moindres pour les autres services écosystémiques. Ce sont les conclusions d’une étude menée au Costa Rica par une équipe du Cirad, du Cifor et du Catie. Des résultats qui pourraient avoir des répercussions sur le choix des zones à protéger dans le cadre des initiatives visant à atténuer les émissions dues à la déforestation comme la REDD (Reducing Emissions from Deforestation and Forest Degradation).

via CIRAD - Actualités / News http://www.cirad.fr/news/all-news-items/articles/2014/science/biodiversite-et-services-ecosystemiques-font-bon-menage

Lab-Made Sugars Aid Diagnosis

Infectious Disease: Synthetic oligosaccharides could solve long-standing brucellosis detection problem



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Lab-Made Sugars Aid Diagnosis

Infectious Disease: Synthetic oligosaccharides could solve long-standing brucellosis detection problem



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Carbonic Acid Crystal Forms Clarified

Researchers identify the α polymorph as the compound’s monomethyl ester



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October 10, 2014 at 01:32PM La qualité au service du développement des filières agroalimentaires de l’océan Indien

4es Journées scientifiques de l'agroalimentaire en Océan indien. Coorganisées par le Cirad.

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October 10, 2014 at 04:16AM Allergy Alert On Undelcared Eggs In Lotte Waffles

LOTTE Confectionery Co., Ltd. (manufacturer), 21-5ka, Yangpyung-dong, Youngdeunpo-gu, Seoul, Korea, is recalling its 1.41 ounce (40g) and 5.64 ounce (160g) packages of Lotte Waffles because they contain undeclared egg ingredients.



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Nobel Prize In Physiology Or Medicine

Awards: John O’Keefe, May-Britt Moser, and Edvard Moser win for discovering the brain’s mapping system



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October 08, 2014 at 11:31PM Oasis Brands, Inc Recalls Cuajada en Hoja 12oz because of Possible Health Risk

Oasis Brands, Inc of Miami, FL is recalling Cuajada en Hoja 12oz with Best By 10/01/14- 10/08/14 and 10/18/14, because it has the potential to be contaminated with Listeria monocytogenes, an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems. Although healthy individuals may suffer only short-term symptoms such as high fever, severe headache, stiffness, nausea, abdominal pain and diarrhea, Listeria infection can cause miscarriages and stillbirths among pregnant women.



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Shaking Up Electron Microscopy

Materials Science: High-resolution vibration information now comes with atomic precision



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Eric Betzig, Stefan Hell, And W. E. Moerner Win 2014 Nobel Prize In Chemistry

Awards: Superresolution fluorescence microscopy has made it possible to capture nanoscale images of cells



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Eric Betzig, Stefan Hell, And W. E. Moerner Win 2014 Nobel Prize In Chemistry

Awards: Superresolution fluorescence microscopy has made it possible to capture nanoscale images of cells



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October 08, 2014 at 02:50PM FDA Issues Final Guidance on Terminology for Veterinary Medicinal Products Adverse Event Reporting

The U.S. Food and Drug Administration issued a final guidance document today to help drug manufacturers submit accurate and consistent adverse event reports related to animal medicinal products, also known as animal drugs.



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October 08, 2014 at 12:38PM Quand la lutte biologique modifie le régime alimentaire des prédateurs

Les plantes de couverture peuvent favoriser la régulation naturelle des ravageurs en permettant aux populations de prédateurs d’augmenter. Mais elles peuvent aussi modifier considérablement le régime alimentaire de ces prédateurs. Une équipe du Cirad vient d’en apporter la preuve en identifiant, grâce à la technique du métabarcoding ADN, les proies ingérées par les prédateurs du charançon du bananier dans les plantations de la Martinique. Une première dans l’utilisation in situ de cette technique d’analyse de l’ADN.

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October 08, 2014 at 10:31AM 15e Rencontres de Virologie Végétale (RVV)

Colloque coorganisé par le Cirad.

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October 08, 2014 at 03:49AM HAR Maspeth Corp RECALLS Jinga brand “Pan Fried Anchovies� BECAUSE OF POSSIBLE HEALTH RISK

HAR Maspeth Corp. of Maspeth, NY, is recalling its 2 ounce and 4 ounce packages of Jinga “Pan Fried Anchovies� due to contamination with Listeria monocytogenes, an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people and others with weakened immune systems.



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Some Atmospheric Nanoparticles Could Have Cosmetic Sources

Atmospheric Chemistry: Siloxanes in personal care products could be source of silicon in ultrafine particulate matter in urban air



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October 07, 2014 at 02:00PM Caution: Using Certain OTC Medicines May Affect Your Driving Ability

Antihistamines and other OTC drugs can impair your ability to drive and operate machinery.



via FDA Consumer Health Information Updates http://ift.tt/1vN6wbq

John O’Keefe, May-Britt Moser, And Edvard Moser Win 2014 Nobel Prize In Physiology Or Medicine

Awards: Researchers discovered the brain’s navigational system



via Chemical & Engineering News: Biological SCENE http://ift.tt/1pHh3kB

Researchers Use Synthetic Biomarkers To Catch A Clot

Medical Diagnostics: New nanoparticle-based assay provides extremely sensitive test of blood clotting in mice



via Chemical & Engineering News: Biological SCENE http://ift.tt/1s3jAvl

Researchers Use Synthetic Biomarkers To Catch A Clot

Medical Diagnostics: New nanoparticle-based assay provides extremely sensitive test of blood clotting in mice



via Chemical & Engineering News: Analytical SCENE http://ift.tt/1pHea3r

October 06, 2014 at 03:30PM Le Cirad fête la science

Les scientifiques sont sur le pont pour la Fête de la science que ce soit en métropole ou en outre-mer (à des dates différées).

via CIRAD - Actualités / News http://ift.tt/1usqOc9

Molecular Mixers

Scientists engineer light-driven molecular motors to create a stir



via Chemical & Engineering News: Analytical SCENE http://ift.tt/1rQF3VI