Friday, May 30, 2014

Fog Clearing On TIC10 Drug Development Mix-Up

Synthesis: Structural misassignment stems from long-standing use of incorrect recipe to prepare anticancer agent



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Los Angeles Airport Pollutes City Air For Miles Downwind

Air Quality: Elevated concentrations of ultrafine particulate matter from jet emissions extend at least 10 miles east of the airport, raising health concerns for area residents



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Building Biobased Copolymers

Sustainability: Chemists can now make cost-competitive polyesters entirely from biobased monomers



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Thursday, May 29, 2014

May 29, 2014 at 04:50PM FDA’s MedWatch Safety Alerts: April 2014

FDA warns consumers about undeclared drugs found in weight loss pills, a sexual enhancement product, and pain relief pills.



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How To Build A Biobased Copolymer

Sustainability: Chemists can now make cost-competitive polyesters entirely from biobased monomers



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May 29, 2014 at 03:00PM Indoor Tanning Raises Risk of Melanoma: FDA Strengthens Warnings for Sunlamp Products

To help protect consumers and inform them about the risks of indoor tanning, FDA is strengthening its regulation of sunlamp products and UV lamps and requiring that sunlamp products carry a visible, black box warning stating that sunlamp products should not be used on people under 18 years of age.



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May 28, 2014 at 06:00AM Enter our reader appreciation giveaway to win veterinarian Nick Trout's new novel

Like us on Facebook to enter the drawing—five lucky winners will receive an autographed copy of Dog Gone, Back Soon.



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Chemists Report Potent Inhibitors Of Little-Studied Arthritis Enzyme

Medicinal Chemistry: ATP analogs could serve as drug leads for pseudogout



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Wednesday, May 28, 2014

May 29, 2014 at 04:46AM Navitas Naturals Issues Voluntary Recall for Organic Sprouted Chia Seed Powder Products

Navitas Naturals, the Superfood Company is voluntarily recalling products which contain Organic Sprouted Chia Powder due to possible health risks related to Salmonella contamination. “We have chosen to voluntarily recall products containing Organic Sprouted Chia Powder with the goal of utmost safety for our consumers� stated Zach Adelman, Navitas Naturals CEO.



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May 28, 2014 at 08:52PM American Importing Co, Inc Issues Allergy Alert On Undeclared Almonds Mispacked As Cinnamon Crunch Granola

American Importing Co, Inc of Minneapolis, MN is voluntarily recalling a limited number of packages of a single lot of Cinnamon Crunch Granola because they may contain undeclared almonds. People who have an allergy or sensitivity to almonds run the risk of serious or lifethreatening allergic reaction if they consume this product.



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May 28, 2014 at 08:37PM Pet Center, Inc. Voluntary Recall of 3 oz bag of Lamb Crunchy’s Because of Possible Health Risk

Pet Center, Inc of Los Angeles, CA. is voluntarily recalling its 3 oz bag of Lamb Crunchy’s dog treats (LAM-003) (UPC# 727348200038) with date code 122015 product of USA, because it has the potential to be contaminated with Salmonella.



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May 28, 2014 at 08:34PM Rome Packing Co., Inc. Recalls Minced Crab Meat Because Of Possible Health Risk

Rome Packing Co., Inc. has issued a voluntary recall of Ocean’s Catch brand minced crab meat after routine product sampling by the company determined some of the finished products may have been contaminated with Listeria monocytogenes bacteria.



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May 28, 2014 at 08:37PM Pet Center, Inc. Voluntary Recall of 3 oz bag of Lamb Crunchy’s Because of Possible Health Risk

Pet Center, Inc of Los Angeles, CA. is voluntarily recalling its 3 oz bag of Lamb Crunchy’s dog treats (LAM-003) (UPC# 727348200038) with date code 122015 product of USA, because it has the potential to be contaminated with Salmonella.



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May 28, 2014 at 06:00AM Dechra partners with new manufacturer for ophthalmic ointments

Consistent supply of two products will begin with more to follow.



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May 28, 2014 at 03:00PM Sometimes Drugs and the Liver Don't Mix

May is Hepatitis Awareness Month, a fitting time to focus on liver health. Medications pose a potential danger and have been responsible for drug-induced liver injuries. FDA is working to prevent those injuries.



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Tuesday, May 27, 2014

Urine Test Could Diagnose Hard-To-Spot Infertility In Men

Medical Diagnostics: Levels of five metabolites in urine can distinguish infertile men with normal-looking semen from the more fecund



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Urine Test Could Diagnose Hard-To-Spot Infertility In Men

Medical Diagnostics: Levels of five metabolites in urine can distinguish infertile men with normal-looking semen from the more fecund



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May 27, 2014 at 06:00AM Million-dollar lawsuit filed against Texas veterinarian

Couple accuse Millard Lucien Tierce, who allegedly kept sick dogs for experiments, of gross negligence.



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May 21, 2014 at 10:31AM International Encounters 'Family Farming and Research' - Montpellier, 1st to 3rd June 2014

Over the course of two days, Montpellier welcomes more than 250 major actors in the fields of agriculture and rural life. Farmers, leaders of rural peoples' organisations and NGOs, policy makers, development workers, researchers and concerned citizens will arrive from the four corners of the planet to reflect on the challenges of research on, for and with family farming.






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May 27, 2014 at 03:00PM Lupus Therapies Continue to Evolve

May is National Lupus Awareness Month, a time to think about lupus and the challenges it presents to patients. Learn about this chronic, autoimmune disease and the promise of future therapies.



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May 27, 2014 at 02:31PM François Pouget, est nommé directeur général délégué aux ressources et aux dispositifs (DGD-RD) du Cirad

François Pouget prendra ses fonctions le 2 juin prochain. Il succède à Patrick Herbin qui assurait l’intérim de la direction depuis le départ de Jacques Pagès nommé conseiller scientifique auprès de l’ambassadeur de France à la FAO.






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May 27, 2014 at 02:09PM Family farming: the brochure is now available in English

The brochure Agricultures familiales, une chance pour la planète , produced for the general public to mark the 2014 Paris International Agricultural Show and the International Year of Family Farming, is now available in English.






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May 27, 2014 at 11:35AM Bois et forêts des tropiques is now entirely free on line

Articles in the journal Bois et forêts des tropiques, published by CIRAD, are now freely accessible on the journal's website. This change fits in with the policy of open access CIRAD has been supporting for almost ten years now.






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May 27, 2014 at 02:09PM Agriculture familiale : la brochure grand public disponible en anglais

Conçue pour un large public à l'occasion dans le cadre de l’année internationale de l’agriculture familiale, la brochure Agricultures familiales, une chance pour la planète…, est désormais disponible en version anglaise.






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May 27, 2014 at 11:44AM Bois et forêts des tropiques No. 319 - Special issue on family farming

A special issue of the journal Bois et forêts des tropiques devoted to family farming, and the first for which all articles are available free of charge on the journal's website.






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May 27, 2014 at 11:44AM Bois et forêts des tropiques N°319 - Spécial Agriculture familiale

Un numéro spécial de la revue Bois et forêts des tropiques entièrement consacré à l'agriculture familiale ainsi que le 1er dont tous les articles sont gratuitement accessibles sur le site web de la revue.






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May 27, 2014 at 11:35AM Bois et forêts des tropiques devient entièrement gratuit en ligne

Les articles de la revue Bois et forêts des tropiques, éditée par le Cirad, sont désormais gratuitement accessibles sur le site web de la revue. Une évolution qui va de pair avec la politique de libre accès que soutient le Cirad depuis déjà près de dix ans.






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Monday, May 26, 2014

May 26, 2014 at 04:42PM Journées Mycotoxines

Coorganisées par le Cirad.






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May 20, 2014 at 10:57AM Bananas at risk from Panama disease

Identified for the first time in 1874 in Australia, Panama disease, otherwise known as Fusarium wilt, is now affecting almost all tropical and subtropical banana-producing regions.






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May 22, 2014 at 02:12PM The mycotoxins that contaminate our food

On 5 and 6 June 2014 the National Mycotoxins Days will be held at the University of Montpellier 2. This event was launched in 2010 in Montpellier by CIRAD’s QualiSud joint research unit (Integrated Approach to Food Quality), which will organise the meeting in 2014.






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May 23, 2014 at 10:16AM The Agropolis International dossier on family farming is now available in English

The Agropolis International dossier on family farming is now available in English. It contains examples of the research conducted over many years by the Agropolis International scientific community in Montpellier, Languedoc-Roussillon, "on" and "for" family farming.






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May 26, 2014 at 11:31AM Filmez 2014, année internationale des agricultures familiales

Il y a un an, le Cirad donnait carte blanche aux étudiants qui s’apprêtaient à découvrir leur terrain de stage dans les pays du Sud. Six futurs diplômés, issus d’Agrosup Dijon, de l’Iedes Paris I et de Supagro Montpellier, ont saisi l’opportunité offerte par le Cirad : devenir reporters ! A leur retour, ils nous ont offert des témoignages, interviews, points de vue sur l’agriculture familiale en Afrique ou en Amérique Latine, désormais regroupés dans un DVD. Autant de regards précieux et originaux à retrouver sur cette agriculture où vie de famille et production agricole sont intimement mêlées.






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May 20, 2014 at 11:59AM Desert locusts: a wide-ranging study has solved the mystery of solitary populations

With the first locust invasions beginning in East Africa this year, researchers from CIRAD are questioning several widely held beliefs about solitary insects. The results of w ide-ranging genetic study with numerous African partners were both surprising and novel. Desert locusts were thought to be sedentary during their solitary phase, whereas they can travel several kilometres. Populations were considered fragile, whereas they are actually perfectly suited to their environment and have a significant ability to recolonize, along with substantial and sustainable genetic diversity. Solitary populations, which travel fast, can very quickly discover zones in which the conditions are almost ripe for reproduction. These results radically alter our vision of solitary desert locust populations. This is a boost to invasion surveillance and prevention strategies






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Sunday, May 25, 2014

Old Paintings’ Egg White Coatings Unveiled

Protective proteins prevent oxygen diffusion, scientists discover



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To Uncover Substrates For Mystery Enzymes, Fragment-Based Approaches May Be A Poor Fit

Strategy’s success for finding enzyme inhibitors doesn’t translate to substrates in new study



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Diabetes-Related Enzyme Modulates Insulin, Amylin, And Glucagon

Inhibition of insulin-degrading enzyme by synthetic macrocycle suggests strategy for type 2 diabetes treatment



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Steve Perrin

Characterizing animal models isn’t glamorous, says ALS Therapy Development Institute’s CEO, but it’s critical to bringing medicines to market



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Old Paintings’ Egg White Coatings Unveiled

Protective proteins prevent oxygen diffusion, scientists discover



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Image-Guided Drug Design

Research team incorporates brain scans into iterative process to find drugs capable of penetrating blood-brain barrier



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Big Tussle Over Tiny Particles

In peer-reviewed papers and on blogs, researchers argue over the existence of striped coatings on nanoparticles



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Friday, May 23, 2014

May 24, 2014 at 03:52AM Sun Tree LLC Recalls 12oz Packaged California Grown Shelled Walnuts Due to Possible Health Risk

Sun Tree LLC is voluntarily recalling walnuts comprising of 46 cases of 24 count 12oz produce bags, California Grown Shelled Walnuts, Lot No. 42720, Best by 12/11/2014 UPC code, 69887507806, because it has been determined that there is a possibility of contaminated with Listeria monocytogenes. Listeria monocytogenes is an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems. Although healthy individuals may suffer only short-term symptoms such as high fever, severe headache, stiffness, nausea, abdominal pain and diarrhea, Listeria infection can cause miscarriages and stillbirths among pregnant women.



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May 23, 2014 at 11:13PM Belleville Farmer’s Market Recalls Shelled Walnuts Because of Possible Health Risk

Belleville Farmer’s Market of Belleville, IL is recalling its packages of Shelled Walnuts because they have the potential to be contaminated with Listeria monocytogenes, an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems. Although healthy individuals may suffer only short-term symptoms such as high fever, severe headache, stiffness, nausea, abdominal pain and diarrhea, Listeria infection can cause miscarriages and stillbirths among pregnant women.



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May 23, 2014 at 06:00AM Mizzou veterinary student wins Bayer Excellence in Communication Award

Bayer awards $70,000 to veterinary students at 27 schools.



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May 23, 2014 at 09:36PM Brunkow Cheese Issues Allergy Alert On Undeclared Soy In Jalapeno Pepper Raw Milk Cheddar Cold Pack Cheese

Brunkow Cheese of Darlington, Wisconsin, is voluntarily recalling its 8 ounce tubs of Fayette Creamery brand Jalapeno Pepper Raw Milk Cheddar Cold Pack Cheese Spread because they may contain an undeclared soy ingredient. People who have allergies or severe sensitivity to soy run the risk of serious or life-threatening allergic reaction if they consume these products.



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May 23, 2014 at 06:37PM Whole Foods Market Recalls Thai Soba Noodle Salad in Five States, Due to Undeclared Allergen

Whole Foods Market is recalling Thai Soba Noodle Salad sold in all stores in five states due to an undeclared soy allergen. The product has a Use by Date of: 5/25/14.



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Composting Could Offer Low-Cost Way To Dispose Of Disease-Causing Prions

Public Health: In a preliminary study, composting inactivates prion proteins that cause neurological diseases in people and livestock



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May 23, 2014 at 06:00AM Merial beginning to fill back orders for veterinarians waiting on Purevax

Distribution of the feline rabies vaccines stopped in April after irregularities found in product.



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Rethinking Photocatalysis

Catalysis: Study questions conventionally ascribed role of metal particles on semiconductors



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EPA Targets Refinery Pollution

Air Toxics: Industry blasts proposed emission rule as unjustified and costly



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May 22, 2014 at 10:18AM Sustainable cocoa production: learning from agroforestry

In order to meet growing demand for chocolate products, numerous initiatives have been launched over the last 10 years with a view to increasing cocoa production. These initiatives continue to promote the input-intensive model advocated since the 1960s, even though this model has reached its agronomic, socio-economic, and environmental limits. Hence the proposal to learn from agroforestry in order to develop the current model: introducing fruit and forest tree species into cocoa plantations contributes to the agro-ecological intensification of cocoa production, while improving flexibility and resilience, which are essential to smallholder farmers, who grow 95% of the world’s cocoa.






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May 23, 2014 at 10:16AM Le dossier d'Agropolis International sur les agricultures familiales disponible en anglais

Le dossier d'Agropolis International consacré aux agricultures familiales est désormais disponible en version anglaise. Il regroupe des exemples de recherches menées, depuis de nombreuses années, par la communauté scientifique d’Agropolis International à Montpellier en Languedoc-Roussillon, « sur » et « pour » les agricultures familiales.






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Thursday, May 22, 2014

May 22, 2014 at 11:58PM Kind Healthy Snacks Issues Allergy Alert Due to Potential Presence of Peanut Protein in Strong and Kind Bars and Kind Healthy Grains Maple Pumpkin Seeds Bars

NEW YORK - KIND Healthy Snacks (KIND) is voluntarily recalling STRONG and KIND bars as well as KIND Healthy Grains Maple Pumpkin Seeds with Sea Salt bars after learning that, contrary to KIND's strict quality specifications, its supplier roasted pumpkin seeds using equipment that had also been used to roast peanuts. 'While we know our supplier conducted rigorous allergen cleans before roasting the seeds, they did not perform tests to validate that no peanut particles remained, and KIND takes no chances when it comes to the safety of our consumers,' said John Leahy, President of KIND.



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Tug-of-War Over Promising Cancer Drug Candidate

Drug Discovery: Structure error threatens existing patent and clinical trials



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May 22, 2014 at 10:57PM Appointment of new JVDI editors





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May 22, 2014 at 10:57PM Pooling of porcine fecal samples for quantification of Lawsonia intracellularis by real-time polymerase chain reaction

Procedures in which biological specimens are mixed and tested as 1 sample (pooling) have been applied for various biological specimens and laboratory examinations. The objective of the current study was to investigate agreement between laboratory testing of fecal pools and theoretical values obtained by averaging test results from individual fecal samples in relation to a quantitative polymerase chain reaction (qPCR) test for Lawsonia intracellularis. Ten diarrheic and 10 normal fecal samples were submitted from each of 43 Danish swine herds (n = 860 fecal samples). Pools (n = 43), each containing 20 individual fecal samples from the same herd, were prepared in the laboratory by pooling 10% fecal phosphate buffered saline solutions. All pools and individual fecal samples were subjected to qPCR testing for L. intracellularis. The theoretical number of L. intracellularis in the pools was calculated as the mean number of bacteria from the 20 individual fecal samples contributing to each pool. Agreement between the laboratory testing of pools and theoretical calculations based on individual sample results was evaluated. Pooling resulted in fewer L. intracellularis–positive herds (41.9%) compared with testing 20 fecal samples (53.5%). Agreement between the laboratory and the theoretical pools for dichotomized test results was 100% (95% confidence interval: 91.8–100%). For the quantitative test results, Lin concordance correlation coefficient was 0.997. The mean difference between the laboratory testing and the theoretical values was not different from zero (mean difference = 0.039 log10 bacteria/g feces; P = 0.26).






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May 22, 2014 at 10:57PM Pooling serum to identify cohorts of nonmilking cattle likely to be infected with Bovine viral diarrhea virus by testing for specific antibodies

Testing for specific antibodies against Bovine viral diarrhea virus (BVDV) in pooled serum may present an opportunity to decrease the cost of screening for herds of high seroprevalence and increased likelihood of active infection. Experimental serum pools (n = 280) were created by combining equal aliquots of serum from between 5 and 25 individuals. A further 188 serum pools were generated from field serum samples. All pools and individual sera were tested for BVDV-specific antibodies by enzyme-linked immunosorbent assay (ELISA), according to manufacturer’s instructions. Pools returned repeatable results, with coefficients of variation generally below 10%. The presence of serum from a persistently infected (PI) individual in the pool had no significant effect on the ELISA sample-to-positive (S/P) ratio. The results revealed that a single strong antibody-positive individual could maintain a positive result (at the manufacturer’s threshold) in pools of up to 128, while even a single weak-positive animal would generate a positive result in pools of up to 8. The S/P ratio of the pool was positively related to the within-pool prevalence of antibody-positive individuals. However, as the strength of the individual positive animals contributing to the pool had a large effect on the pool S/P ratio, the S/P ratio could not be used to accurately predict the within-pool prevalence of field serum pools. An alternative method of S/P ratio interpretation was pursued, and a two-graph receiver operating characteristic analysis allowed segregation of pools into low, medium, and high risk with good results when applied to field serum pools.






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May 22, 2014 at 10:57PM Intraerythrocytic iridovirus in central bearded dragons (Pogona vitticeps)

Three adult central bearded dragons (Pogona vitticeps) originating from a commercial breeding facility presented with clinical signs, including anorexia, dehydration, white multifocal lesions on the dorsal aspect of the tongue, blepharospasm, and weight loss. In 1 of 3 lizards, a marked regenerative anemia was noted, and all 3 bearded dragons had erythrocytic intracytoplasmic inclusion bodies. Nine bearded dragons housed in contact also had identical, but fewer intraerythrocytic inclusions. Inclusion bodies examined by electron microscopy had particles consistent with iridoviruses. Attempts to culture the virus were unsuccessful; however, amplification and sequencing of regions of the viral DNA polymerase by polymerase chain reaction confirmed the presence of an iridovirus. One of the bearded dragons died, while the 2 others showing clinical signs were euthanized. The remaining 9 infected bearded dragons of the teaching colony were also euthanized. Postmortem examination revealed a moderate, multifocal, lymphoplasmacytic or mononuclear adenitis of the tongue in the 3 bearded dragons, and a lymphohistiocytic hepatitis with bacterial granulomas in 2 lizards.






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May 22, 2014 at 10:57PM A retrospective study of equine actinobacillosis cases: 1999-2011

Several Actinobacillus spp. are common commensal bacteria of the oral cavity, gastrointestinal tract, and reproductive tract of horses and can cause disease in both foals and adults. The current retrospective study was designed to review Actinobacillus spp. isolated from clinical samples or necropsies of 99 horses during 1999–2011. The cases consisted of 43 foals (<6 months of age), 4 young adults (6 months–2 years), 39 adults (>2 years of age), 2 aborted fetuses, and 11 with unspecified ages. Clinical history, signs, bacterial species isolated, and associated lesions were documented. Actinobacillus spp. were isolated 111 times. The most common isolates were Actinobacillus equuli subsp. equuli (38.7%) and hemolytic Actinobacillus spp. (24.3%). Other isolates were Actinobacillus lignieresii (5.4%), Actinobacillus pleuropneumoniae (1.8%), and unclassified Actinobacillus spp. (28.8%). Actinobacillus equuli subsp. equuli was most commonly isolated from clinical and necropsy cases of septicemia and respiratory disease in both foals and adults. Embolic nephritis, the classical septicemic lesion of equine neonatal actinobacillosis, was also present in several adult septicemic actinobacillosis cases. Predisposing factors such as failure of passive transfer of colostral antibodies as well as concurrent pathogenic bacterial or viral infections were present in numerous actinobacillosis cases. There were many cases, however, for which a predisposing factor or concurrent infection was not documented or apparent, suggesting that Actinobacillus spp. can be primary pathogens under the right circumstances and in the right location.






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May 22, 2014 at 10:57PM Evaluating micronutrient concentrations in liver samples from abortions, stillbirths, and neonatal and postnatal losses in beef calves

The primary objective of the current study was to describe micronutrient concentrations in livers collected during postmortem examination from 501 beef calves and fetuses in western Canada. The most frequently identified deficiencies based on reported ranges for aborted fetuses were magnesium, copper, and vitamin E. For stillborn, neonatal, and postnatal calves, the most common deficiencies were magnesium, vitamin A, and vitamin E. However, for calves that died after 3 days of age, selenium deficiency was also very likely. Concentrations of all micronutrients examined in the study except zinc (P = 0.85) were different among fetuses, stillbirths, and neonatal and postnatal losses. This included liver selenium, copper, manganese, molybdenum, iron, magnesium, vitamin A, and vitamin E (P < 0.01). The percentiles of micronutrient concentrations for each age group, empirical prediction intervals for individual calves, and model predicted confidence intervals to compare with average concentrations from groups of calves were summarized for each age group. Information on cow, calf, and herd management attributes were available for 221 samples from 106 herds collected as part of study 1. Cow age, supplementation history, water quality, and herd location were associated with the concentration of iron, zinc, and molybdenum. The current study is unique in the number of samples included from young calves that were submitted as part of routine surveillance and not based on suspicion of either deficiency or toxicity. Most previous studies have been focused on older animals or fetuses and have contained a mix of beef and dairy animals with little or no information on their supplementation history.






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May 22, 2014 at 10:57PM Significance of ER{alpha}, HER2, and CAV1 expression and molecular subtype classification to canine mammary gland tumor

Canine mammary gland tumor (CMT) and human breast cancer (HBC) share many similarities regarding their risk factors, histological features, and behavior. Despite the increasing evidence of molecular marker expression as a prognostic indicator for HBC, few studies have applied this approach to CMT. The aim of the present study is to evaluate the significance of the expression of estrogen receptor–alpha (ERα), human epidermal growth factor receptor 2 (HER2), and caveolin-1 (CAV1) to the behavior and the clinical outcome of CMT. Additionally, the correlation between subtype classification (luminal A, luminal B, HER2-overexpressing, basal-like, and normal-like) and tumor behavior prognosis were assessed. Canine mammary gland tissues were immunohistochemically stained for ERα, HER2, and CAV1 and evaluated and classified into 5 subtypes on the basis of immunoreactivity. Although there were no statistically significant differences in the molecular marker immunoreactivity of different subtypes, the degree of positive staining for ERα, extranuclear ERα, HER2, and CAV1 showed significant correlations (P < 0.05) with the behavior and prognosis of the tumor. The current study indicates the prognostic value of immunohistochemical staining status of ERα, HER2, and CAV1 for CMT. In addition, some trends were seen in subtype classification on the prognosis of the tumor, implying that, although further analysis is needed, there is potential clinical application of 5-subtype classification for CMT.






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May 22, 2014 at 10:57PM Enzyme-linked immunosorbent assay for coproantigen detection of Trichuris vulpis in dogs

Infections with Trichuris vulpis, the canine whipworm, may be challenging to diagnose even though characteristic bipolar eggs are shed by mature worms and may be recovered from feces. Decreased detection sensitivities because of using flotation solutions with specific gravities <1.3 and a lengthy prepatent period can lessen the diagnostician’s ability to detect infection. Coproantigen detection in feces is becoming an accepted form of diagnosing parasitic infections and can circumvent some of the factors that affect egg recovery. The development of an enzyme-linked immunosorbent assay (ELISA) for the detection of whipworm-specific coproantigens in the feces of dogs with experimental and natural T. vulpis infections is reported herein. Whipworm-specific coproantigens were evidenced in feces from experimentally infected dogs using the newly developed ELISA starting as early as day 23 postinfection, while eggs were not detected in feces until day 69. In addition, 1,156 field fecal samples were tested using fecal flotation methods and the newly developed whipworm ELISA. Of these, 27 samples were found by flotation to be whipworm egg positive, while 35 had detectable antigen on the ELISA. Discrepant results were obtained in 12 samples; 2 egg-positive samples tested ELISA negative, and 10 ELISA-positive samples did not contain detectable egg levels. Using the fecal ELISA for the detection of whipworms in dogs should allow for earlier detection of infection, aid the identification of cases in the face of low egg shedding, and increase detection sensitivity as most commercial laboratories are using flotation solutions not optimal for T. vulpis egg detection.






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May 22, 2014 at 10:57PM Poisoning by Talisia esculenta (A. St.-Hil.) Radlk in sheep and cattle

Talisia esculenta is a tree that produces pitomba, a fruit consumed by human beings in several regions of Brazil. The current study reports 3 outbreaks of poisoning by leaves and fruits of T. esculenta affecting sheep and cattle and the experimental reproduction of the disease in sheep. In the first investigated outbreak, sheep ingested the leaves of the plant; another outbreak affected cattle and sheep that ingested leaves and fruits; and in a third outbreak, sheep ingested only the fruits. The animals developed severe nervous signs, but most recovered. Poisoning was reproduced experimentally in 5 sheep by the administration of 30–60 g of leaves/kg body weight and in 2 sheep with doses of 5 and 10 g of seeds/kg body weight, respectively. No significant necropsy or histologic lesions were found.






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May 22, 2014 at 10:57PM Use of tissue swabbing as an alternative to tissue dissection and lysis prior to nucleic acid extraction and real-time polymerase chain reaction detection of Bovine viral diarrhea virus and Porcine reproductive and respiratory syndrome virus

The use of swabbing to sample tissue samples, prior to nucleic acid extraction and performance of a real-time polymerase chain reaction (PCR) assay, was investigated for the detection of the viral pathogens Bovine viral diarrhea virus (BVDV) and Porcine reproductive and respiratory syndrome virus (PRRSV). The tissue swabbing method involved swabbing recently cut tissues, eluting the swabbed material, and extracting nucleic acid from the eluate prior to PCR amplification. Parallel testing of this method with traditional nucleic acid extraction from tissues, where small pieces of tissue are dissected and digested (typically overnight) in lysis buffer prior to nucleic acid extraction, was carried out for 50 samples for each virus. The results demonstrated that equivalent PCR results were obtained with both methods. It was also shown on a smaller number of samples that equivalent PCR results were also obtained when the lysis step of the swabbing method was reduced to only 2 hr. The ability to remove the overnight step typically associated with processing tissue samples for PCR analysis offers the potential for same-day testing of tissue. Although the current study is preliminary in nature and further validation will be required before adoption for routine use, the results show that tissue swabbing is a promising approach. It offers a convenient, simpler, and less time-consuming alternative to tissue dissection and lysis and has potential advantages for routine laboratory operation and outbreak testing, including easier pooling and sampling of large areas of tissue and carcasses.






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May 22, 2014 at 10:57PM Diagnostic value of tissue monensin concentrations in horses following toxicosis

Two separate incidents of monensin exposure in horses resulting in toxicosis provided insight into the diagnostic value and interpretive criteria of various biological samples. In case 1, 25 horses broke into a shed and ingested feed that was supplemented with 800 g/ton (880 µg/g) of monensin. Within 48 hr, 1 horse had died, 2 developed cardiac arrhythmias, lethargy, and recumbency, and another was euthanized due to severe deterioration. Minimal histologic lesions were noted in the horse that died peracutely, while another showed characteristic lesions of acute cardiomyocyte degeneration and necrosis. Stomach content, heart, liver, urine, and serum revealed various detectable concentrations of monensin in clinically affected and unaffected horses with known exposure. In case 2, a pastured horse had access to a mineral mix containing 1,600 g/ton (1,760 µg/g) of monensin. Within 48 hr, the horse became symptomatic and was euthanized because of severe respiratory distress. Histologic cardiac lesions were minimal but detectable amounts of monensin were found in blood, heart, liver, and stomach contents. In both cases, monensin toxicosis was confirmed with toxicological analysis. These cases demonstrate an overall lack of correlation of monensin concentrations in various biological samples with clinical outcome. However, serum, urine, blood, liver, heart, and stomach content can be tested to confirm exposure. More importantly, the consistently higher concentrations found in heart tissue suggest this is the most useful diagnostic specimen for postmortem confirmation of toxicosis in horses especially in cases in which associated feed cannot be tested for monensin or in cases with no histologic lesions.






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May 22, 2014 at 10:57PM Rapid detection of terbufos in stomach contents using desorption electrospray ionization mass spectrometry

Desorption electrospray ionization mass spectrometry (DESI-MS) is an emerging analytical technique that permits the rapid and direct analysis of biological or environmental samples under ambient conditions. Highlighting the versatility of this technique, DESI-MS has been used for the rapid detection of illicit drugs, chemical warfare agents, agricultural chemicals, and pharmaceuticals from a variety of sample matrices. In diagnostic veterinary toxicology, analyzing samples using traditional analytical instrumentation typically includes extensive sample extraction procedures, which can be time consuming and labor intensive. Therefore, efforts to expedite sample analyses are a constant goal for diagnostic toxicology laboratories. In the current report, DESI-MS was used to directly analyze stomach contents from a dog exposed to the organophosphate insecticide terbufos. The total DESI-MS analysis time required to confirm the presence of terbufos and diagnose organophosphate poisoning in this case was approximately 5 min. This highlights the potential of this analytical technique in the field of veterinary toxicology for the rapid diagnosis and detection of toxicants in biological samples.






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May 22, 2014 at 10:57PM Amino acid differences in cat adrenocorticotropin account for the inability of a human-based immunoradiometric assay to detect the molecule in cat plasma

A commercial immunoradiometric assay kit designed for the measurement of endogenous adrenocorticotropin (ACTH) concentrations in human plasma does not detect the molecule in plasma samples from cats. It was hypothesized that the inability of the assay to detect the molecule was related to variation(s) in the amino acid sequence of cat ACTH, compared with human ACTH. Cat ACTH complementary DNA was cloned from pituitary tissue and sequenced. The deduced structure showed amino acid differences from the human molecule with cat ACTH having a valine instead of alanine at amino acid 32 and a threonine instead of alanine at amino acid 34. Cat and human ACTH were synthesized along with 2 modified peptides containing alanine substitutions at cat ACTH 32 and 34. Only the human ACTH was detected using the commercial kit, indicating that an epitope recognized by one of the antibodies in the assay requires the presence of 2 alanines near the C-terminus of the molecule.






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May 22, 2014 at 10:57PM Lack of association of ABCB4 insertion mutation with gallbladder mucoceles in dogs

The etiology of canine gallbladder mucocele (GBM) has not yet been identified. However, several studies have linked GBM in dogs to particular breeds (Shetland Sheepdogs are commonly implicated), concurrent endocrine disease (hyperadrenocorticism and/or hypothyroidism), and a mutation in the canine ABCB4 gene (ABCB4 1583_1584G), particularly in Shetland Sheepdogs. The current study assessed ABCB4 1583_1584G, in a wider sample of dogs with GBM compared with age and breed-matched controls. ABCB4 1583_1584G was identified in 4 of 8 Shetland Sheepdogs and 13 of 28 other breeds with GBM. ABCB4 1583_1584G was also detected in 9 of 12 Shetland Sheepdogs and 23 of 37 other breeds that did not have GBM. No statistically significant association existed between ABCB4 1583_1584G and the presence of GBM for all dogs combined or for Shetland Sheepdogs alone. In contrast to previously reported findings, the current study did not identify a strong association between ABCB4 1583_1584G and GBM in Shetland Sheepdogs or other breeds.






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May 22, 2014 at 10:57PM Synergistic hemolysis between {beta}-lysin-producing Staphylococcus species and Rothia nasimurium in primary cultures of clinical specimens obtained from dogs

Nonhemolytic isolates of catalase-positive, Gram-positive cocci were observed that produced strong synergistic hemolysis with colonies of Staphylococcus pseudintermedius and Staphylococcus schleiferi subsp. coagulans in primary cultures of clinical specimens from dogs. The isolates appeared similar to nonhemolytic staphylococci but were not identified with conventional biochemical tests or commercial biochemical test kits. Partial 16S ribosomal RNA gene sequences from each of 9 tested isolates were nearly identical to that of Rothia nasimurium. The isolates produced positive Christie–Atkins–Munch–Peterson test reactions with Staphylococcus aureus (ATCC strain 25923) and Staphylococcus intermedius Hajek (ATCC strain 49052). The latter was identified in the current study as S. pseudintermedius. Rothia nasimurium appears to be a previously unreported commensal organism in dogs. Its potential significance as an opportunistic contributor to polymicrobial infections in dogs is not known.






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May 22, 2014 at 10:57PM Disseminated Blastomyces dermatitidis, genetic group 2, infection in an alpaca (Vicugna pacos)

A 7-year-old, female Huacaya alpaca presented with a 3-week history of left-sided head tilt and mild ataxia. Despite aggressive supportive therapy with empirical antibiotic, anti-inflammatory, thiamine, and anthelminthic therapy, neurologic signs progressed to a right-sided head tilt, positional nystagmus, and episodes of severe ataxia and obtundation. On necropsy, discrete expansile to poorly delineated infiltrative masses with tan, creamy to grumous exudate were observed in the right petrous temporal bone, right middle and inner ear, right cerebellum and medulla as well as in lung, kidney, liver, spleen, lymph nodes, and the gastrointestinal tract. Impression cytology and histology revealed a myriad of intralesional yeast, 10–25 μm in diameter, with double-contoured walls, granular protoplasm, and broad-based budding. Culture characteristics, including conidial morphology and temperature-dependent yeast phase transformation, were consistent with Blastomyces sp. Positive Blastomyces antigenuria was identified on a postmortem sample of urine. Microsatellite typing and sequencing of the internal transcribed spacer region 2 identified the infecting strain as a genetic group 2 isolate of Blastomyces dermatitidis. The present report of camelid blastomycosis adds intracranial blastomycosis to the differential list for camelid neurologic disease in endemic regions.






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May 22, 2014 at 10:57PM Immunohistochemical characterization of multicentric hepatocholangiocellular adenoma in a pig

Three spherical opaque-white tumor nodules were found in close proximity to each other in the liver of a breeding sow, postslaughter, at a veterinary food inspection. The tumor nodules were circumscribed and histologically consisted of discrete hepatocellular and cholangiocellular nests, in association with polygonal-to-oval–shaped cells with slight cellular atypia. Immunohistochemically, all cellular components were negative for carcinoembryonic antigen, but positive for p53. Both cholangiocytes and oval-shaped cells were immunoreactive to anti-cytokeratin antibodies AE1/AE3 and MNF116. In addition, cholangiocytes were exclusively immunoreactive to anti-cytokeratin antibody CAM5.2, and hepatocytes were positive for MNF116 and hepatocyte paraffin 1. All neoplastic cells were positive for the hepatic progenitor cell markers, α-1-fetoprotein, sal-like protein 4, and epithelial cell adhesion molecule. From these results, the present case was diagnosed as hepatocholangiocellular adenoma, arising from epithelial cells of the canals of Hering.






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May 22, 2014 at 10:57PM Mammary diffuse fibroadenomatoid hyperplasia in water buffalo (Bubalus bubalis): three cases

The current report describes 3 rare cases of mammary diffuse fibroadenomatoid hyperplasia in water buffalo (Bubalus bubalis). All of the animals were between 10 and 12 months of age. Grossly, the lesions consisted of severe diffuse swelling with homogeneous large masses in the udder. Surgical removal of the masses was curative. Microscopically, there was severe hyperplasia of the mammary epithelium and numerous well-differentiated and mildly pleomorphic acini and their associated ducts. Moderate proliferation of the fibrous connective tissue and the myoepithelial cells near the proliferating acini was also evident. The hyperplastic epithelial cells exhibited positive immunostaining for cytokeratin, estrogen receptors, and progesterone receptors. In addition, the myoepithelial cells displayed moderate positivity for alpha smooth muscle actin. Based on the clinical, morphologic, and immunohistochemical findings, a diagnosis of mammary diffuse fibroadenomatoid hyperplasia with probable hormonal influence was made.






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May 22, 2014 at 10:57PM Mucosal lesions and mortality associated with the use of a ferric sulfate poultry litter amendment product

Within hours of chick delivery, acute mortality and mucosal lesions were reported on 2 northeast Georgia broiler farms that had applied a ferric sulfate litter amendment product. Histological evaluation of the larynx, tongue, and surrounding stroma revealed multifocal areas of necrosis or degeneration of the oral mucosa, acute focal necrotizing cellulitis, and the presence of a brown-black pigmented material adhered to affected epithelial and mucosal surfaces. Multifocal to diffuse ventricular koilin degeneration and acute hemorrhage was also demonstrated in association with pigmented adherent material on affected surfaces. Perls iron stain revealed that adherent material on affected tissues was strongly positive for iron. An experiment was designed to reproduce clinical signs, lesions, and mortality using the same litter amendment product. The ferric sulfate litter amendment was confirmed as the causative agent.






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May 22, 2014 at 10:57PM Canine parvovirus 2c infection in a cat with severe clinical disease

Canine parvovirus 2 (CPV-2) is considered the main pathogen responsible for acute gastroenteritis in dogs, causing vomiting and hemorrhagic enteritis mainly. However, infection in cats by CPV variants causes clinical signs similar to Feline panleukopenia virus. The current study reports a case of CPV-2c in a domestic cat, in Portugal. The findings suggest that more surveys are needed to know the true prevalence and significance of cats in CPV epidemiology worldwide.






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May 22, 2014 at 10:57PM Use of immunohistochemical staining and electron microscopy to aid in diagnosis of soft tissue sarcomas associated with the fetlock joint in two horses

Soft tissue sarcomas of the equine distal limb associated with joints, sheaths, or bursae have rarely been reported. Accurate diagnosis of these tumors is challenging in both human beings and veterinary species. Immunohistochemical staining and transmission electron microscopy have been used in human beings to reduce misdiagnosis. The current report describes 2 mature horses presenting with lameness and swelling associated with the dorsal aspect of the metacarpo(tarso)phalangeal joint. In both cases, surgical excision was performed with subsequent histological analysis of the masses to determine the tissue of origin. In both cases, immunohistochemical staining and transmission electron microscopy aided the definitive diagnosis of fibrosarcoma associated with the fetlock joints of 2 horses.






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May 22, 2014 at 10:57PM Retinal microvascular damage and vasogenic edema produced by Clostridium perfringens type D epsilon toxin in rats

When the brain is exposed to large circulating levels of Clostridium perfringens type D epsilon toxin (EXT), microvascular damage with resulting severe, generalized, vasogenic edema seems to be principally responsible for the ensuing acute, and frequently fatal, neurologic disorder. However, although the blood–retinal barrier resembles in many respects the blood–brain barrier, retinal changes in livestock with acute epsilon intoxication have not, to the authors’ knowledge, been previously reported. In rats given an acute dose of ETX, retinal microvascular endothelial injury led to widespread vasogenic edema as assessed immunohistochemically by marked plasma albumin extravasation. As laboratory rodents are a good model of the domestic livestock disease produced by ETX, it is probable that the latter sustain some visual deficit when exposed to large doses of this potent neurotoxin.






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May 22, 2014 at 03:00PM Skin Cancer Patients Have More Treatment Options

Science is finding new ways to attack cancer on different fronts. Since 2011, FDA has approved five drugs for melanoma and other skin cancers, giving patients more specialized tools, better treatment, better outcomes and a longer life.



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Self-Assembling Nanoparticles Sneak Antisense RNA Into Cells

Nanomedicine: Nanoparticles with a polymer core and a nucleic acid shell regulate gene expression in human cells



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May 22, 2014 at 06:00AM NexGard effective against two additional types of ticks

FDA approves Merial label claims for black-legged, Lone star ticks.



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May 22, 2014 at 03:00PM Always Tired? You May Have Sleep Apnea

Obstructive sleep apnea has been linked to high blood pressure, heart attacks, strokes, car accidents, work-related accidents and depression. Learn about this disorder and how to treat it.



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Patent Picks: 3-D Printing

A look at recent patenting activity in 3-D printing in biomedical engineering applications, brought to you by C&EN and CAS



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Turning A Troubling Contaminant Into A Simple Sugar

Bioremediation: A three-enzyme process converts the industrial pollutant 1,2,3-trichloropropane into glycerol



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May 22, 2014 at 02:12PM Ces mycotoxines qui contaminent nos aliments…

Du 5 au 6 juin 2014 se dérouleront à l’Université Montpellier 2, les Journées nationales Mycotoxines , initiées en 2010 à Montpellier par l’UMR Qualisud du Cirad, qui en portera l’organisation en 2014.






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May 22, 2014 at 10:18AM Production durable de cacao : s'inspirer de l'agroforesterie

Pour satisfaire la consommation croissante de produits chocolatés, de nombreuses initiatives ont été lancées depuis une décennie afin d’augmenter la production de cacao. Ces initiatives continuent de promouvoir le modèle intensif en intrants préconisé depuis les années 1960, alors que ce modèle a atteint ses limites agronomiques, socio-économiques et environnementales. D’où la proposition de s’inspirer de l’agroforesterie pour faire évoluer le modèle actuel : introduire des arbres fruitiers et forestiers dans les cacaoyères contribue à l’intensification agroécologique de la cacaoculture, tout en apportant souplesse et résilience, nécessaires aux petits agriculteurs, qui produisent 95 % du cacao mondial.






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Wednesday, May 21, 2014

May 22, 2014 at 01:27AM Sherman Produce Recalls Bulk and Packaged Walnuts Due to Possible Health Risk

St. Louis-based Sherman Produce is voluntarily recalling walnuts comprising of 241 cases of bulk walnuts packaged in 25 lb bulk cardboard boxes and Schnucks brand 10 oz trays with UPC 00338390032 with best by dates 03/15 and 04/15 because the products are potentially contaminated with Listeria monocytogenes. Listeria monocytogenes is an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems.



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May 21, 2014 at 06:00AM Shortage of Apoquel, new veterinary pruritus drug, to continue until 2015

Zoetis: Existing patients can continue treatment but no new orders are being accepted.



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May 21, 2014 at 06:00AM Visits may be down, but veterinary spending is going up

Pet expenditures exceed expectations in 2013; forecasters expect more growth in 2014.



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Peptide Monitoring Could Aid Cancer Treatment





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Peptide Monitoring Could Aid Cancer Treatment





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Tug Of War Over Promising Cancer Drug Candidate

Drug Discovery: Structure error threatens existing patent and clinical trials



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May 21, 2014 at 03:00PM FDA is Vigilant About Keeping Your Pets Safe

You may know that the FDA works to keep foods and drugs safe for you and your family, but you may not realize the agency does much the same for your pets. Learn how, and what you can do to help.



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May 21, 2014 at 10:31AM Rencontres internationales « AGRICULTURES FAMILIALES ET RECHERCHE » à Montpellier, 1er au 3 juin 2014

Montpellier accueille pendant deux jours plus de 250 acteurs de l’agriculture et de la ruralité. Agriculteurs, responsables d’organisations paysannes, responsables d’ONGs, décideurs politiques, agents de développement, chercheurs, citoyens engagés, ils viennent des 4 coins du monde pour réfléchir aux enjeux de recherche, sur, pour et avec les agricultures familiales. Plus largement, ils jugeront de la place du monde de la recherche académique dans l’invention et la mise en œuvre des modèles agricoles de demain.






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Tuesday, May 20, 2014

May 20, 2014 at 06:00AM FDA approves chewable flea-tick preventive from Merck

Bravecto approved to kill ectoparasites for 12 weeks in single dose.



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May 20, 2014 at 06:20PM Middle East Bakery, Inc. Issues Allergy Alert on Undeclared Milk in Market Basket Dairy-free, Gluten-free Pancakes

Middle East Bakery of Lawrence, MA is recalling all lots of Market Basket Dairy-Free, Gluten-Free Pancakes, because they may contain undeclared milk. People who have an allergy or severe sensitivity to milk run the risk of serious or life-threatening allergic reaction if they consume these products.



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Carbon Dots Shine Brightly In Every Color

Nanomaterials: One-step process yields color-tunable carbon nanoparticles for use in biological sensing and imaging



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May 20, 2014 at 02:00PM Protecting Your Vision: Facts and Fiction

May is Healthy Vision month, and a good time to examine the facts�and fiction�surrounding healthy vision. Take a look at these common statements about eye safety to find out: Fact or fiction?



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May 20, 2014 at 11:59AM Criquets pèlerins : une étude d’envergure perce le mystère des populations solitaires

Alors que les premières invasions de criquets frappent cette année l’Afrique orientale, des chercheurs du Cirad remettent en cause nombre d’hypothèses portant sur le criquet solitaire. Les résultats issus d’une étude génétique d’envergure menée en collaboration avec de nombreux partenaires africains sont surprenants et novateurs. Dans sa phase solitaire, on le croyait sédentaire. Il parcourt au contraire des kilomètres. On supposait ses populations fragiles. Elles sont pourtant parfaitement adaptées à leur environnement et présentent une capacité de recolonisation élevée et une diversité génétique à la fois forte et durable. Les populations solitaires, qui se déplacent rapidement, peuvent alors découvrir très vite les zones devenant favorables à la reproduction. Ces résultats modifient radicalement la vision que l’on avait des populations de criquets pèlerins solitaires. Ils permettront de renforcer la stratégie de surveillance et de prévention des invasions.






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May 20, 2014 at 11:54AM Douze responsables d’organismes de recherche et d’universités alertent leurs concitoyens après la relaxe des « faucheurs » de Colmar

Douze responsables d’organismes de recherche et d’universités (CEA, CNRS, CPU, Inria, ANR, Universcience, Cirad, Irstea, Ifremer, IRD, Inserm, BRGM) expriment leur inquiétude dans une déclaration commune, face aux conséquences de la relaxe par la Cour d’appel de Colmar des 54 «faucheurs volontaires» ayant détruit une parcelle de vigne OGM expérimentale de l’INRA. Selon eux, ce jugement remet en cause la possibilité de conduire des expérimentations sur des sujets faisant l’objet de controverses sociétales. Retrouvez ci-dessous le texte complet de la déclaration.






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May 20, 2014 at 10:57AM La maladie de Panama se rappelle aux bananes

Identifiée pour la première fois en 1874 en Australie, la maladie de Panama ou Fusariose (Fusarium Wilt en anglais) se manifeste aujourd’hui dans presque toutes les zones tropicales et subtropicales de production de banane.






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Monday, May 19, 2014

May 20, 2014 at 12:05AM Kraft Foods Group Voluntarily Recalls Select Cottage Cheese Products Due to Out-of-Standard Storage Temperatures

Kraft Foods Group is voluntarily recalling select Knudsen Cottage Cheese, Breakstone’s Cottage Cheese, Simply Kraft Cottage Cheese, and Daily Chef Cottage Cheese products. Some ingredients used in these products were not stored in accordance with Kraft’s temperature standards.



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May 19, 2014 at 09:30PM WhiteWave Foods Issues Allergy Alert on Undeclared Almondmilk in Half Gallon Silk Light Original Soymilk Containers

WhiteWave Foods is voluntarily recalling half gallon containers of Silk Light Original Soymilk because they may contain undeclared almondmilk. People who have an allergy or sensitivity to almond run the risk of serious or life threatening allergic reaction if they consume this product.



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May 19, 2014 at 06:40PM Allergy Alert on Undeclared Milk in Pancakes

American Waffle Company of Clayton, Delaware is voluntarily recalling 480 cases of Gluten Free Blueberry Pancakes with Best By or Sell By 07/31/15 because the product contains undeclared milk. People who have an allergy or severe sensitivity to milk may be at risk of serious or life threatening allergic reaction if they consume this product.



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May 19, 2014 at 03:00PM How Sweet It Is: All About Sugar Substitutes

Some people use high-intensity sweeteners as a substitute for table sugar. There will soon be a new one available to U.S. consumers. FDA has approved advantame, which is 20,000 times sweeter than sugar.



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May 19, 2014 at 05:24PM FDA Provides Latest Information on Jerky Pet Treat Investigation

FDA Provides Latest Information on Jerky Pet Treat Investigation



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May 19, 2014 at 01:53PM FDA to Retain Current Small Numbers of Animals for Minor Use in Major Species

The U.S. Food and Drug Administration (FDA) announced today that, following a reassessment, it will continue using the same “small numbers of animals” in a major species to determine whether an intended use of a new animal drug in a major species of animal qualifies as a minor use.



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Sunday, May 18, 2014

α-Ketoglutarate Could Be A Target For Age-Related Disease Treatments





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Energy Metabolite Extends A Worm’s Life





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Bacteria Template Their Own Cell-Binding Polymers





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Fate Of Gulf Oil Spill Methane Reexamined





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NMR-EPR Combo Yields RNA-Protein Structure

Spectroscopy: Approach illuminates how translation activator works



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α-Ketoglutarate Could Be A Target For Age-Related Disease Treatments





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NMR-EPR Combo Yields RNA-Protein Structure

Spectroscopy: Approach illuminates how translation activator works



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Self-Assembling Molecule Nurtures Stem Cells

Supramolecular Chemistry: A glycoconjugate self-assembles to form a gel that promotes mouse embryonic stem cell growth and development



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Friday, May 16, 2014

May 16, 2014 at 06:00AM Compounded drug may have killed four horses, FDA reports

10 horses in Kentucky and Florida affected by EPM treatment; agency is investigating.



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May 16, 2014 at 10:50AM Salon du chocolat

Avec la participation du Cirad.






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May 16, 2014 at 10:38AM 4e Assises de la biodiversité

Avec la participation du Cirad.






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Thursday, May 15, 2014

May 15, 2014 at 11:19PM FDA Alerts Horse Owners and Veterinarians About Adverse Events Associated with Certain Unapproved Compounded Drugs in Horses

The U.S. Food and Drug Administration is alerting horse owners and veterinarians that two lots of compounded combination drug products containing pyrimethamine and toltrazuril, used to treat the neurologic disease Equine Protozoal Myeloencephalitis (EPM), have been associated with adverse events in ten horses.



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May 15, 2014 at 06:00AM Veterinary surgeons group introduces ACVS Surgery Summit

New name for annual event represents evolution, increased benefits to veterinarians, organizers say.



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May 15, 2014 at 04:24PM Le Foncier Agricole : usages, tensions et régulations

Un colloque coorganisé par la Société française d'économie rurale (Sfer), Irstea, le Cirad et l’Inra.






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May 15, 2014 at 03:20PM Influenza Virus Vaccine for the 2009-2010 Season

Vaccine lot release information updated on 1/20/2010.



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Wednesday, May 14, 2014

May 15, 2014 at 02:13AM Bravo® Issues Nationwide Recall of Pet Food for Dogs and Cats

Manchester, CT – Bravo is recalling select lots and product(s) of Bravo Pet Food because they have the potential to be contaminated with Listeria monocytogenes. Listeria monocytogenes is an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems.



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May 15, 2014 at 02:13AM Bravo® Issues Nationwide Recall of Pet Food for Dogs and Cats

Manchester, CT – Bravo is recalling select lots and product(s) of Bravo Pet Food because they have the potential to be contaminated with Listeria monocytogenes. Listeria monocytogenes is an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems.



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Multifaceted Collaboration Solves Natural Product Puzzle

Biosynthesis coupled with computational studies unravel the origins of a set of bioactive fungal alkaloids



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May 14, 2014 at 05:34PM 3e Conférence scientifique mondiale sur l’Agriculture Climato-Intelligente

Organisée par le Cirad, l’Inra, l’IRD et Agropolis International avec le soutien du programme CCAFS du GCRAI, de l'Université de Wageningen (Pays-Bas) et de l'Université de Californie à Davis (USA).

Appel à communications ouvert jusqu'au : 15 Juin 2014

Date limite pour les inscriptions à tarif préférentiel : 15 Décembre 2014






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May 14, 2014 at 03:56PM Plantations forestières : mélanger les espèces pour une meilleure exploration du sol par les racines

Pour intensifier la production de bois tout en préservant l’environnement, l’une des solutions consiste à mettre en place des plantations mixtes, qui associent espèces sélectionnées pour les caractéristiques de leur bois et légumineuses, ces dernières, grâce la fixation d’azote atmosphérique, permettant de réduire les apports d’engrais azoté. Un projet de recherches, coordonné par le Cirad, a évalué le potentiel de ces plantations forestières et étudié comment la biodiversité influe sur les processus souterrains de facilitation et de compétition entre espèces. Des processus mal connus, qui jouent pourtant un rôle fondamental dans l’accès aux ressources en eau et en nutriments, et, en définitive, dans la production de bois.






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Tuesday, May 13, 2014

May 14, 2014 at 05:13AM US Trading Company Voluntary Recall of Crushed Chili Powder Because of Possible Health Risk

US Trading Company of Hayward, CA is recalling its Dragonfly Brand Crushed Chili Powder in 6.3 ounce plastic tubs with lot code 359XP, because it has the potential to be contaminated with Salmonella, an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems.



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May 13, 2014 at 06:13PM Surma Distributors LLC, Issues Alert On Undeclared Sulfites In Haque Brand Golden Raisins

Surma Distributors LLC., located at 1075 Flushing Ave., Brooklyn, NY 11237, is recalling HAQUE brand Golden Raisins because the product contains undeclared sulfites.



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May 13, 2014 at 05:01PM Domega Ny International Co Ltd Issues Allergy Alert On Undecleared Eggs In Brilliant Cake With Filling Milk (biscuits)

recalling BRILLIANT CAKE WITH FILLING MILK (BISCUITS) because it contains undeclared eggs. Consumers who have allergies to eggs run the risk of serious or life-threatening allergic reactions if they consume this product.



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Inexpensive Paper Device Detects Explosives In Seconds

Forensics: Using a color-change reaction, the device can detect nanogram quantities of trinitro aromatic explosives



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May 13, 2014 at 06:00AM AAVMC partners with Zoetis for veterinary scholarship program

More than $3.6 million awarded since program?s inception five years ago.



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Monday, May 12, 2014

May 12, 2014 at 11:36PM Domega NY International Co LTD Issues Allergy Alert On Undeclared Peanuts In YF Sesame Flavor Cracker

DOMEGA NY INTERNATIONAL CO LTD, 47-57 BRIDGEWATER STREET BROOKLYN NY 11222 is recalling YF Sesame Flavor Cracker because it contains undeclared peanuts. People who have allergies to peanuts run the risk of serious or life-threatening allergic reactions if they consume this product.



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May 12, 2014 at 11:04PM Stonyfield Extends Voluntary Recall of YoBaby Peach/Pear Yogurt Cup 6-packs to 271 Additional Stores in 6 Western States

Organic yogurt maker Stonyfield is extending its voluntary recall of YoBaby Peach/Pear yogurt in 4 oz. 6-pack cups with the code date June 05 2014 (UPC 052159701161). The recall now includes an additional 1,344 6-packs shipped to 271 more stores, mostly Safeway and Fred Meyer stores, in the following states: Oregon, Washington, Montana, Idaho, Alaska, and Northern California.



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Trove Of Toxic Mercury Lurks In Arctic Sea Ice

Environment: Ice-core analysis shows more methylmercury will enter Arctic food chain as climate change speeds up ice melt



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May 12, 2014 at 09:51PM Strong America Limited ISSUES ALLERGY ALERT ON UNDECLARED EGG IN “Golden Smell Hotpot Meat Ball Medley”

Strong America Limited of Long Island City, New York is recalling its 1 pound package of “Golden Smell Hotpot Meat Ball Medley” food treats because they may contain undeclared eggs.



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May 12, 2014 at 06:00AM Feline medicine, Fairness to Pet Owners Act and more in the dvm360 Five

Special report from CVC Washington, D.C.



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May 12, 2014 at 06:00AM Texas veterinarian accused of keeping dogs for experiments in 'deplorable' conditions

Dr. Millard Tierce suspected of animal cruelty after former employee notified clients their pet was not euthanized as agreed upon.



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May 12, 2014 at 06:00PM How Long Should You Take Certain Osteoporosis Drugs?

According to an FDA review, further investigation is needed on the long-term risks and benefits of bisphosphonates, drugs used to treat osteoporosis.



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May 12, 2014 at 06:00AM Feline medicine, Fairness to Pet Owners Act and more in the dvm360 Five

Special report from CVC Washington, D.C.



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Sunday, May 11, 2014

Protein Target Of Clot-Preventing Drugs Seen For The First Time

P2Y12 receptor’s X-ray structure reveals protein pockets that may prove useful in drug design



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Young Blood Rejuvenates Old Mice

At least one protein in the blood of young rodents reverses brain and muscular degradation in elderly rodents



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Protein Target Of Clot-Preventing Drugs Seen For The First Time

P2Y12 receptor’s X-ray structure reveals protein pockets that may prove useful in drug design



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Element 117 Repeat

Superheavy element is now eligible to become the new end of the periodic table, if the findings are judged to be conclusive



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Bead Hopper Loads Up Microfluidic Devices

Method turns polymer bead sedimentation problem into a way to load beads into microfluidic devices for high-throughput experiments



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A New Way Of Fracking

With hydraulic fracturing an established practice, oil and gas firms turn to reducing the technology’s environmental footprint



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Friday, May 9, 2014

May 08, 2014 at 06:00AM dvm360 iPad publication: Issue 35 is now available

With a feature on how to cope with negative reviews, 7 tips to fill down time, what to do if an employee is stealing and a study of a cat's responsiveness to an owner's voice; plus videos, photos, quizzes and more.



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May 09, 2014 at 01:00PM Help FDA Keep Kids from Using Tobacco

FDA monitors compliance with federal tobacco laws through surveillance, inspections, and investigations. Help FDA in your community by reporting potential violations of the law.



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Thursday, May 8, 2014

May 09, 2014 at 02:36AM STE Fromagere Du Livradois Voluntarily Recalls Raclette Cheese and Montboissie Cheese for Possible Health Risk

Ste Fromagere du Livradois of Fournols, France is recalling Haut Livradois brand Raclette and Montboissie cheeses lot#350 because they have the potential to be contaminated with Salmonella, an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems.



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May 08, 2014 at 08:32PM MDA Issues Consumer Advisory for Five Flavors of Lily Bloom’s Kitchen Poparoons Milk Ingredient was Undeclared on Labels

The Minnesota Department of Agriculture (MDA) is notifying consumers that Lily Bloom’s Kitchen of Fridley, Minnesota, has issued an allergy alert for undeclared allergens in five flavors of Poparoons, a macaroon-type confection. The label did not declare milk as an ingredient.



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Polymer Nanoparticles Deliver Genes To Brain Tumor Cells

Nanomedicine: Genes carried by biodegradable polymer particles are efficiently expressed only in brain cancer cells in mice, but not in healthy brain cells



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May 08, 2014 at 02:00PM Five Tips for New Moms

Mother’s Day is May 11, an exciting time for new moms. But moms (and dads) of babies 12 months and younger can also have some worries. FDA medical officers offer health suggestions



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Wednesday, May 7, 2014

Bacteria Given Expanded Genetic Code

Synthetic Biology: Modified bacteria are first cells to copy DNA with three base pairs



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May 07, 2014 at 02:00PM Fighting Allergy Season with Medications

Consumers have more options than ever for relief of allergy symptoms and treatment of allergic diseases in the form of FDA-approved medications. Learn more about these medications, including three newly approved sublingual (under the tongue) prescription medications to treat hay fever caused by certain grass pollens and short ragweed pollen.



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Tuesday, May 6, 2014

May 06, 2014 at 06:00AM Portia Stewart named Firstline editor, dvm360.com team channel director

Award-winning editor focuses on providing tools, insights for veterinary team members.



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May 06, 2014 at 02:55PM FDA Approves HALAMID Aqua to Treat Disease in Freshwater Fish

The U.S. Food and Drug Administration (FDA) has approved HALAMID® Aqua, a chloramine-T powder for immersion, to treat bacterial gill disease in freshwater-reared salmonids, external columnaris disease in walleye, and external columnaris disease in freshwater-reared warm water finfish.



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Monday, May 5, 2014

May 06, 2014 at 03:40AM Pacific Organic Produce Announce Voluntary Recall of Mangos Due to Possible Health Risk

Pacific Organic Produce, San Francisco, CA is voluntarily recalling a limited number of cases of organic Tommy Atkins mangos (PLU numbers 94051 & 94959) that were sold under the Purity Organic brand between the dates of April 14, 2014 and May 2, 2014 due to a possible health risk from Listeria monocytogenes.



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May 05, 2014 at 07:36PM Sixdog Investments Voluntarily Recalls Eggs Because of Possible Health Risk

Sixdog Investments, LLC is voluntarily recalling some cases of their certified organic eggs, because of the potential they are contaminated with Salmonella. This voluntary field action was initiated because of routine testing results, and not because of illness to date from consumption.



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May 05, 2014 at 01:00PM Can an Aspirin a Day Help Prevent a Heart Attack?

Scientific evidence shows that aspirin can prevent heart attack or stroke in some people but not in everyone. And it can cause unwanted side effects. Where do you fit in?



via FDA Consumer Health Information Updates http://ift.tt/1ojkKxt

Sunday, May 4, 2014

Supercritical Fluid Chromatography Seeks New Users

Decades-old separation method has reemerged as an analytical tool, but it remains unclear whether it can gain broader acceptance



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Studying Chemical Warfare Agents Directly

A surface science instrument adapted for highly toxic compounds permits study of environmental and decontamination effects



via Chemical & Engineering News: Analytical SCENE http://ift.tt/RjWHmQ

Antibiotic May Sidestep Resistance

Drug Discovery: Bacteria may find agent’s mechanism hard to circumvent



via Chemical & Engineering News: Biological SCENE http://ift.tt/1uouElH

Why Monoclonal Antibody Drugs Get Sticky

Material could serve as water-based ‘grease’ in artificial joints, reducing wear



via Chemical & Engineering News: Biological SCENE http://ift.tt/1uouE5g

Polymer Mimics Natural Joint Lubricant

Material could serve as water-based ‘grease’ in artificial joints, reducing wear



via Chemical & Engineering News: Biological SCENE http://ift.tt/1uouB9G

Tomato Plants’ Chemical Weapons

Plants under attack unleash volatile alcohol, which neighboring plants can transform into defensive glycoside



via Chemical & Engineering News: Biological SCENE http://ift.tt/1uouyul